Arid4b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arid4b
AT-rich interaction domain 4B
MGI:2137512

29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arid4b^tm1Alb/Arid4b⁺ involves: 129S7/SvEvBrd * C57BL/6	genetic imprinting	J:113402
Arid4b^tm1Alb/Arid4b^tm1.1Mywu Tg(Amh-cre)8815Reb/0 involves: 129S7/SvEvBrd * C57BL/6J * FVB/N	abnormal seminiferous tubule epithelium morphology	J:233398
	abnormal seminiferous tubule morphology	J:233398
	abnormal Sertoli cell development	J:233398
	abnormal spermatid morphology	J:233398
	abnormal spermatogenesis	J:233398
	abnormal spermatogonia morphology	J:233398
	abnormal testis physiology	J:233398
	arrest of spermatogenesis	J:233398
	azoospermia	J:233398
	decreased epididymis weight	J:233398
	decreased male germ cell number	J:233398
	decreased testis weight	J:233398
	dilated seminiferous tubule	J:233398
	increased circulating follicle stimulating hormone level	J:233398
	increased circulating luteinizing hormone level	J:233398
	increased testis apoptosis	J:233398
	male infertility	J:233398
	seminiferous tubule degeneration	J:233398
	small epididymis	J:233398
	small testis	J:233398
Arid4b^tm1Alb/Arid4b^tm1Alb involves: 129S7/SvEvBrd * C57BL/6	embryonic lethality, complete penetrance	J:113402
Arid4b^{tm1b(EUCOMM)Wtsi}/Arid4b⁺ C57BL/6N-Arid4b^{tm1b(EUCOMM)Wtsi}/Bay	abnormal retina morphology	J:211773
	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	increased bone mineral density	J:211773
	increased lean body mass	J:211773
	increased thigmotaxis	J:211773
Arid4b^{tm1b(EUCOMM)Wtsi}/Arid4b^{tm1b(EUCOMM)Wtsi} C57BL/6N-Arid4b^{tm1b(EUCOMM)Wtsi}/Bay	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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