Mrpl3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrpl3
mitochondrial ribosomal protein L3
MGI:2137204

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrpl3^dcr/Mrpl3^dcr B6(Cg)-Mrpl3^dcr/Dcr	astrocytosis	J:167846
	brain vacuoles	J:167846
	cachexia	J:167846
	normal cardiovascular system phenotype	J:167846
	disheveled coat	J:167846
	hippocampal neuron degeneration	J:289566
	hunched posture	J:167846
	impaired learning	J:289566
	impaired spatial learning	J:289566
	increased susceptibility to ischemic brain injury	J:167846
	lethargy	J:167846
	nervous	J:167846
	neurodegeneration	J:167846, J:289566
	premature death	J:167846
Mrpl3^em1(IMPC)J/Mrpl3⁺ C57BL/6NJ-Mrpl3^em1(IMPC)J/J	increased hemoglobin content	J:211773
Mrpl3^em1(IMPC)J/Mrpl3⁺ C57BL/6NJ-Mrpl3^em1(IMPC)J/J	increased mean corpuscular hemoglobin concentration	J:211773
Mrpl3^em1(IMPC)J/Mrpl3^em1(IMPC)J C57BL/6NJ-Mrpl3^em1(IMPC)J/J	abnormal egg cylinder morphology	J:279207
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic growth arrest	J:279207
	embryonic lethality prior to organogenesis	J:211773, J:279207
	embryonic lethality, complete penetrance	J:279207
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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