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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fam20c
FAM20C, golgi associated secretory pathway kinase
MGI:2136853
90 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Fam20ctm1.1Cqi/Fam20ctm1.1Cqi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA
abnormal chondrocyte differentiation J:185208
abnormal circulating protein level J:185208
abnormal limb long bone morphology J:185208
abnormal long bone diaphysis morphology J:185208
abnormal long bone epiphyseal plate morphology J:185208
abnormal long bone epiphyseal plate proliferative zone J:185208
abnormal osteocyte morphology J:185208
abnormal skeleton morphology J:185208
abnormal vertebral column morphology J:185208
abnormal vitamin D level J:185208
decreased body size J:185208
decreased body weight J:185208
decreased bone mineral density J:185208
decreased bone mineralization J:185208
decreased chondrocyte apoptosis J:185208
decreased chondrocyte proliferation J:185208
decreased circulating phosphate level J:185208
decreased compact bone thickness J:185208
delayed bone ossification J:185208
delayed cranial suture closure J:185208
delayed endochondral bone ossification J:185208
female infertility J:185208
flat face J:185208
fragile skeleton J:185208
impaired osteoblast differentiation J:185208
increased circulating parathyroid hormone level J:185208
increased width of hypertrophic chondrocyte zone J:185208
male infertility J:185208
osteomalacia J:185208
postnatal growth retardation J:185208
rickets J:185208
short snout J:185208
small cranium J:185208
Fam20ctm1.1Cqi/Fam20ctm1.1Cqi
Tg(Col1a1-cre)2Bek/0
involves: 129S6/SvEvTac * CD-1
abnormal cementum morphology J:225679
abnormal osteocyte canaliculus morphology J:225679
abnormal osteocyte dendritic process morphology J:225679
abnormal osteocyte lacuna morphology J:225679
abnormal osteocyte lacunocanalicular system morphology J:225679
abnormal osteocyte morphology J:225679
abnormal periodontal ligament morphology J:225679
alveolar process atrophy J:225679
decreased body height J:225679
decreased bone mineral density J:225679
decreased bone volume J:225679
decreased circulating phosphate level J:225679
decreased collagen level J:225679
dental pulp inflammation J:225679
detached junctional epithelium J:225679
periodontal ligament necrosis J:225679
periodontal pocket J:225679
periodontium inflammation J:225679
tooth abscess J:225679
Fam20ctm1Lex/Fam20ctm1Lex
involves: 129S5/SvEvBrd * C57BL/6
abnormal bone structure J:186384
abnormal cued conditioning behavior J:186384
abnormal dental pulp cavity morphology J:186384
abnormal dentin development J:186384
abnormal dentin morphology J:186384
abnormal epiphyseal plate morphology J:186384
abnormal femur morphology J:186384
abnormal glomerular capsule parietal layer morphology J:186384
abnormal jaw morphology J:186384
abnormal lacrimal gland physiology J:186384
abnormal maxilla morphology J:186384
abnormal motor capabilities/coordination/movement J:186384
abnormal postnatal growth/weight/body size J:186384
abnormal prepulse inhibition J:186384
abnormal salivary gland morphology J:186384
abnormal skeleton morphology J:186384
abnormal tooth hard tissue morphology J:186384
abnormal tooth morphology J:186384
abnormal tooth root morphology J:186384
abnormal trabecular bone morphology J:186384
abnormal vertebrae morphology J:186384
absent bone trabeculae J:186384
absent enamel J:186384
apical tooth abscess J:186384
conical molar J:186384
decreased body length J:186384
decreased body weight J:186384
decreased bone mineral content J:186384
decreased bone mineral density J:186384
decreased circulating calcium level J:186384
decreased circulating phosphate level J:186384
decreased compact bone thickness J:186384
decreased Leydig cell number J:186384
decreased locomotor activity J:186384
decreased trabecular bone thickness J:186384
decreased trabecular bone volume J:186384
dental pulp necrosis J:186384
distended abdomen J:186384
extramedullary hematopoiesis J:186384
fragile skeleton J:186384
impaired balance J:186384
impaired hearing J:186384
increased circulating alkaline phosphatase level J:186384
mandibular hyperostosis J:186384
osteosclerosis J:186384
postnatal growth retardation J:186384
postnatal lethality, incomplete penetrance J:186384
small molars J:186384

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory