Crb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crb1
crumbs family member 1, photoreceptor morphogenesis associated
MGI:2136343

25 phenotypes from 8 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crb1^em1Jnk/Crb1^em1Jnk involves: C57BL/6J * SJL	abnormal retina outer limiting membrane morphology	J:293375
Crb1^em2Jnk/Crb1^em2Jnk involves: C57BL/6J * SJL	abnormal retina outer limiting membrane morphology	J:293375
Crb1^em3Jnk/Crb1^em3Jnk involves: C57BL/6J * SJL	abnormal photoreceptor inner segment morphology	J:293375
	abnormal retina outer limiting membrane morphology	J:293375
	retina photoreceptor degeneration	J:293375
Crb1^em4Jnk/Crb1^em4Jnk involves: C57BL/6J * SJL	abnormal photoreceptor inner segment morphology	J:293375
	abnormal retina outer limiting membrane morphology	J:293375
	retina photoreceptor degeneration	J:293375
Crb1^rd8+em1Mvw/Crb1^rd8 C57BL/6NJ-Crb1^rd8+em1Mvw	normal vision/eye phenotype	J:206789
Crb1^rd8/Crb1^rd8 B6.Cg-Crb1^rd8	normal vision/eye phenotype	J:85459
Crb1^rd8/Crb1^rd8 B6.Cg-Crb1^rd8 Jak3⁺/Boc	abnormal retina morphology	J:265859
	abnormal retina pigment epithelium morphology	J:265859
	abnormal retina pigmentation	J:265859
	abnormal retina vasculature morphology	J:265859
	retina neovascularization	J:265859
	retina spots	J:265859
Crb1^rd8/Crb1^rd8 involves: C3HfB6/Ga * C57BL/6 * CAST/EiJ	abnormal retina morphology	J:85459
Crb1^rd8/Crb1^rd8 involves: C57BL/6N	abnormal retina pigment epithelium morphology	J:182353
Crb1^rd8/Crb1^rd8 involves: C57BL/6N	retina degeneration	J:182353
Crb1^rd8/Crb1^rd8 STOCK Crb1^rd8/J	abnormal Muller cell morphology	J:85459
	abnormal ocular fundus morphology	J:85459
	abnormal photoreceptor inner segment morphology	J:85459
	abnormal retina morphology	J:85459
	abnormal retina outer limiting membrane morphology	J:85459
	abnormal retina photoreceptor morphology	J:85459
	decreased retina photoreceptor cell number	J:85459
	photoreceptor outer segment degeneration	J:85459
	short photoreceptor inner segment	J:85459
	short photoreceptor outer segment	J:85459
	thin retina outer nuclear layer	J:85459
Crb1^tm1Wij/Crb1^tm1Wij involves: 129P2/OlaHsd * C57BL/6	abnormal Muller cell morphology	J:92068
	abnormal retina photoreceptor morphology	J:92068
	photosensitivity	J:92068
	retina degeneration	J:92068
Crb1^tm1Wij/Crb1^tm2Wij involves: 129P2/OlaHsd * C57BL/6	abnormal retina inner nuclear layer morphology	J:117415
	abnormal retina morphology	J:117415
	abnormal retina outer nuclear layer morphology	J:117415
	abnormal retina photoreceptor layer morphology	J:117415
	retina fold	J:117415
	thin retina outer nuclear layer	J:117415
Crb1^tm2Wij/Crb1^tm2Wij either: B6.129P2-Crb1^tm2Wij or (involves: 129P2/OlaHsd * C57BL/6)	preweaning lethality, complete penetrance	J:117415

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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