Aff4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aff4
AF4/FMR2 family, member 4
MGI:2136171

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aff4^em1(IMPC)Mbp/Aff4⁺ C57BL/6N-Aff4^em1(IMPC)Mbp/MbpMmucd	abnormal caudal vertebrae morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	decreased body length	J:211773
	increased freezing behavior	J:211773
	increased grip strength	J:211773
	small kidney	J:211773
Aff4^em1(IMPC)Mbp/Aff4^em1(IMPC)Mbp C57BL/6N-Aff4^em1(IMPC)Mbp/MbpMmucd	abnormal blood vessel morphology	J:211773
	abnormal craniofacial morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	anophthalmia	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Aff4^tm1Nosa/Aff4^tm1Nosa involves: 129P2/OlaHsd * C57BL/6	abnormal mating frequency	J:100030
	abnormal pulmonary alveolus morphology	J:100030
	abnormal respiration	J:100030
	arrest of spermatogenesis	J:100030
	azoospermia	J:100030
	embryonic growth retardation	J:100030
	embryonic lethality during organogenesis, incomplete penetrance	J:100030
	normal hematopoietic system phenotype	J:100030
	increased body weight	J:100030
	increased seminal vesicle weight	J:100030
	male infertility	J:100030
	neonatal lethality, incomplete penetrance	J:100030
	small epididymis	J:100030
	small testis	J:100030

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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