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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pard3
par-3 family cell polarity regulator
MGI:2135608
25 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
either: FVB.129-Pard3tm1Shoh Krt14tm1(cre)Wbm or (involves: 129P2/OlaHsd * 129S4/SvJae)
decreased incidence of tumors by chemical induction J:192905
decreased tumor growth/size J:192905
decreased tumor latency J:192905
increased incidence of tumors by chemical induction J:192905
increased metastatic potential J:192905
increased tumor growth/size J:192905
increased tumor latency J:192905
normal neoplasm J:192905
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
abnormal epidermal melanocyte morphology J:240961
abnormal hair follicle melanocyte morphology J:240961
increased incidence of tumors by chemical induction J:240961
increased melanocyte number J:240961
Krt14tm1(cre)Wbm/Krt14+
Pard3tm1Shoh/Pard3tm1Shoh
Tg(HIST1H2BB/EGFP)1Pa/0
involves: 129 * C57BL/6J
abnormal melanocyte morphology J:240961
Pard3tm1.1Shoh/Pard3tm1.1Shoh
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
abnormal heart development J:146415
abnormal telencephalon development J:146415
atrium hypoplasia J:146415
edema J:146415
embryonic growth retardation J:146415
embryonic lethality during organogenesis, complete penetrance J:146415
enlarged heart atrium J:146415
short tail J:146415
ventricular hypoplasia J:146415
Pard3tm1b(KOMP)Wtsi/Pard3+
C57BL/6N-Pard3tm1b(KOMP)Wtsi/H
abnormal optic disk morphology J:211773
decreased lean body mass J:211773
decreased red blood cell distribution width J:211773
Pard3tm1b(KOMP)Wtsi/Pard3tm1b(KOMP)Wtsi
C57BL/6N-Pard3tm1b(KOMP)Wtsi/H
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory