Ifitm5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ifitm5
interferon induced transmembrane protein 5
MGI:1934923

48 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ifitm5^em1Pmof/Ifitm5⁺ involves: CD-1	abnormal bone marrow cavity morphology	J:255349
	abnormal bone ossification	J:255349
	abnormal compact bone morphology	J:255349
	abnormal intramembranous bone ossification	J:255349
	abnormal limb morphology	J:255349
	abnormal long bone diaphysis morphology	J:255349
	abnormal neurocranium morphology	J:255349
	abnormal osteoblast physiology	J:255349
	abnormal osteoclast morphology	J:255349
	abnormal rib morphology	J:255349
	abnormal thoracic cage morphology	J:255349
	abnormal trabecular bone morphology	J:255349
	absent compact bone	J:255349
	bowed radius	J:255349
	bowed tibia	J:255349
	bowed ulna	J:255349
	clavicle hypoplasia	J:255349
	decreased alkaline phosphatase activity	J:255349
	decreased bone mineralization	J:255349
	disorganized long bone epiphyseal plate	J:255349
	impaired osteoblast differentiation	J:255349
	increased width of hypertrophic chondrocyte zone	J:255349
	mandible hypoplasia	J:255349
	neonatal lethality, complete penetrance	J:255349
	short limbs	J:255349
	short mandible	J:255349
Ifitm5^tm1Nha/Ifitm5^tm1Nha C57BL/6-Ifitm5^tm1Nha	abnormal clavicle morphology	J:215966
	abnormal cranium morphology	J:215966
	abnormal ilium body morphology	J:215966
	abnormal mandible morphology	J:215966
	abnormal premaxilla morphology	J:215966
	abnormal skeleton morphology	J:215966
	bowed radius	J:215966
	bowed tibia	J:215966
	bowed ulna	J:215966
	decreased length of long bones	J:215966
	decreased litter size	J:215966
	postnatal lethality, incomplete penetrance	J:215966
	prenatal lethality, incomplete penetrance	J:215966
	small clavicle	J:215966
	thin frontal bone	J:215966
Ifitm5^tm1Pmof/Ifitm5^em1Pmof involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal limb morphology	J:255349
Ifitm5^tm1Pmof/Ifitm5^tm1Pmof involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal trabecular bone morphology	J:264160
	decreased alkaline phosphatase activity	J:264160
	decreased body weight	J:264160
	decreased bone trabecula number	J:264160
	decreased bone volume	J:264160
	decreased compact bone area	J:264160
	decreased compact bone thickness	J:264160
	decreased trabecular bone volume	J:264160
	increased bone trabecular spacing	J:264160
	increased osteoid volume	J:264160
	short femur	J:264160
	normal skeleton phenotype	J:264160

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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