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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ube2n
ubiquitin-conjugating enzyme E2N
MGI:1934835
15 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Ube2ntm1Aki/Ube2ntm1Aki
involves: 129P2/OlaHsd * C57BL/6
abnormal B cell physiology J:112287
abnormal humoral immune response J:112287
abnormal spleen marginal zone morphology J:112287
decreased B cell number J:112287
decreased B cell proliferation J:112287
decreased immunoglobulin level J:112287
decreased marginal zone B cell number J:112287
increased B cell apoptosis J:112287
Ube2nGt(OST374154)Lex/Ube2n+
involves: 129S5/SvEvBrd * C57BL/6
abnormal leukocyte physiology J:120846
abnormal macrophage physiology J:120846
decreased B cell proliferation J:120846
decreased susceptibility to endotoxin shock J:120846
decreased T cell proliferation J:120846
Ube2nGt(OST374154)Lex/Ube2nGt(OST374154)Lex
involves: 129S5/SvEvBrd * C57BL/6
embryonic lethality between implantation and somite formation, complete penetrance J:120846
Ube2ntm1Aki/Ube2ntm1Aki
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:112287
Ube2ntm1Aki/Ube2ntm1Aki
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6
abnormal macrophage physiology J:112287
Ube2ntm2Aki/Ube2ntm2Aki
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality during organogenesis, complete penetrance J:112287

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory