Lias Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lias
lipoic acid synthetase
MGI:1934604

17 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lias^{Gt(OST266609)Lex}/Lias^{Gt(OST266609)Lex} involves: 129S5/SvEvBrd * C57BL/6J	preweaning lethality, complete penetrance	J:103485
Lias^nehe/Lias^nehe C3Fe.B6-Lias^nehe	abnormal brain morphology	J:163880
	abnormal prechordal plate morphology	J:163880
	dilated heart	J:163880
	embryonic growth retardation	J:163880
	embryonic lethality during organogenesis, complete penetrance	J:163880
	forebrain hypoplasia	J:163880
	microcephaly	J:163880
	open neural tube	J:163880
	rostral body truncation	J:163880
	telencephalon hypoplasia	J:163880
Lias^nehe/Lias^nehe involves: C3HeB/FeJ * C57BL/6J	decreased forebrain size	J:98216
	embryonic lethality during organogenesis, complete penetrance	J:98216
	exencephaly	J:98216
Lias^nehe/Lias^tm1Mae involves: 129S6/SvEvTac * C57BL/6J	embryonic growth retardation	J:163880
Lias^nehe/Lias^tm1Mae involves: 129S6/SvEvTac * C57BL/6J	rostral body truncation	J:163880
Lias^tm1Mae/Lias⁺ either: 129S6/SvEvTac-Lias^tm1Mae or (involves: 129S6/SvEvTac * C57BL/6J)	decreased glutathione level	J:101368
Lias^tm1Mae/Lias^tm1Mae either: 129S6/SvEvTac-Lias^tm1Mae or (involves: 129S6/SvEvTac * C57BL/6J)	decreased embryo size	J:101368
	embryonic growth arrest	J:101368
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:101368

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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