Rbfox2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
MGI:1933973

46 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rbfox2^tm1.1Dblk/Rbfox2^tm1.1Dblk E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J	abnormal craniofacial bone morphology	J:279139
	abnormal frontal bone morphology	J:279139
	abnormal nasal bone morphology	J:279139
	abnormal palatal mesenchymal cell proliferation	J:279139
	absent palatine bone horizontal plate	J:279139
	normal cardiovascular system phenotype	J:279139
	cleft secondary palate	J:279139
	decreased bone ossification	J:279139
	normal endocrine/exocrine gland phenotype	J:279139
	frontal bone hypoplasia	J:279139
	neonatal lethality, complete penetrance	J:279139
	palatal shelves fail to meet at midline	J:279139
	normal skeleton phenotype	J:279139
	small mandible	J:279139
Rbfox2^tm1.1Dblk/Rbfox2^tm1.1Dblk Pax3^tm1(cre)Joe/0 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J	abnormal axial skeleton morphology	J:279139
	abnormal craniofacial bone morphology	J:279139
	abnormal craniofacial morphology	J:279139
	abnormal frontal bone morphology	J:279139
	abnormal hypoglossal nerve morphology	J:279139
	abnormal nasal bone morphology	J:279139
	abnormal neurocranium morphology	J:279139
	abnormal oculomotor nerve morphology	J:279139
	abnormal palatal mesenchymal cell proliferation	J:279139
	abnormal rostral-caudal body axis extension	J:279139
	abnormal spine curvature	J:279139
	abnormal trochlear nerve morphology	J:279139
	absent palatine bone horizontal plate	J:279139
	atelectasis	J:279139
	normal cardiovascular system phenotype	J:279139
	cleft secondary palate	J:279139
	decreased bone ossification	J:279139
	ectopic bone	J:279139
	normal endocrine/exocrine gland phenotype	J:279139
	frontal bone hypoplasia	J:279139
	fusion of vertebral bodies	J:279139
	normal muscle phenotype	J:279139
	neonatal lethality, complete penetrance	J:279139
	palatal shelves fail to meet at midline	J:279139
	respiratory distress	J:279139
	respiratory failure	J:279139
	small mandible	J:279139
	small thoracic cavity	J:279139
	subcutaneous edema	J:279139
	thin dermal layer	J:279139
Rbfox2^tm1.1Dblk/Rbfox2^tm1.1Dblk Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL	abnormal locomotor activation	J:181631
	abnormal neuron physiology	J:181631
	abnormal posture	J:181631
	abnormal Purkinje cell migration	J:181631
	normal behavior/neurological phenotype	J:176189
	decreased body weight	J:181631
	decreased cerebellar granule cell precursor proliferation	J:181631
	ectopic Purkinje cell	J:181631
	hydrocephaly	J:181631
	increased neuron apoptosis	J:181631
	increased Purkinje cell number	J:181631
	lethality, incomplete penetrance	J:181631
	postnatal lethality, incomplete penetrance	J:181631
	small cerebellum	J:181631
	thin cerebellar molecular layer	J:181631

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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