Letm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Letm1
leucine zipper-EF-hand containing transmembrane protein 1
MGI:1932557

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Letm1^{Gt(CC0204)Wtsi}/Letm1⁺ 129S.129P2-Letm1^{Gt(CC0204)Wtsi}	abnormal amino acid metabolism	J:222017
	abnormal brain morphology	J:222017
	abnormal embryo development	J:222017
	abnormal enzyme/coenzyme activity	J:222017
	abnormal glucose homeostasis	J:222017
	abnormal liver physiology	J:222017
	abnormal mitochondrial physiology	J:222017
	normal craniofacial phenotype	J:222017
	decreased embryo size	J:222017
	decreased heart weight	J:222017
	decreased oxygen consumption	J:222017
	embryonic growth retardation	J:222017
	embryonic lethality during organogenesis, incomplete penetrance	J:222017
	increased susceptibility to pharmacologically induced seizures	J:222017
Letm1^{Gt(CC0204)Wtsi}/Letm1^{Gt(CC0204)Wtsi} 129S.129P2-Letm1^{Gt(CC0204)Wtsi}	embryonic lethality, complete penetrance	J:222017
Letm1^{Gt(DD0926)Wtsi}/Letm1⁺ 129S.129P2-Letm1^{Gt(DD0926)Wtsi}	abnormal amino acid metabolism	J:222017
	abnormal brain morphology	J:222017
	abnormal embryo development	J:222017
	abnormal enzyme/coenzyme activity	J:222017
	abnormal glucose homeostasis	J:222017
	abnormal liver physiology	J:222017
	abnormal mitochondrial physiology	J:222017
	normal craniofacial phenotype	J:222017
	decreased embryo size	J:222017
	decreased heart weight	J:222017
	decreased oxygen consumption	J:222017
	embryonic growth retardation	J:222017
	embryonic lethality during organogenesis, incomplete penetrance	J:222017
	increased susceptibility to pharmacologically induced seizures	J:222017
Letm1^{Gt(DD0926)Wtsi}/Letm1^{Gt(DD0926)Wtsi} 129S.129P2-Letm1^{Gt(DD0926)Wtsi}	embryonic lethality, complete penetrance	J:222017

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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