Tmem108 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem108
transmembrane protein 108
MGI:1932411

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem108^{tm1b(EUCOMM)Wtsi}/Tmem108^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tmem108^{tm1b(EUCOMM)Wtsi}/Ics	abnormal auditory brainstem response	J:211773
	abnormal cornea morphology	J:211773
	decreased lean body mass	J:211773
	increased bone mineral content	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased total body fat amount	J:211773
	limb grasping	J:211773
Tmem108^tm1Lex/Tmem108^tm1Lex involves: 129S5/SvEvBrd	abnormal CNS synaptic transmission	J:239156
	abnormal dendritic spine morphology	J:239156
	abnormal dentate gyrus neuron dendrite morphology	J:239156
	abnormal excitatory postsynaptic currents	J:239156
	abnormal hippocampus granule cell morphology	J:239156
	abnormal miniature excitatory postsynaptic currents	J:239156
	abnormal spatial working memory	J:239156
	decreased excitatory postsynaptic current amplitude	J:239156
	decreased prepulse inhibition	J:239156
	impaired contextual conditioning behavior	J:239156
	reduced sensorimotor gating	J:239156

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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