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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Egln3
egl-9 family hypoxia-inducible factor 3
MGI:1932288
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Egln1tm1.1Brei/Egln1tm1.1Brei
Egln3tm2Fong/Egln3tm2Fong
Tg(CD68-icre)1Bwlx/0
involves: 129S6/SvEvTac * C57BL/6 		neonatal lethality J:194598
polycythemia J:194598
Egln1tm1Kael/Egln1tm1Kael
Egln3tm1Vlcg/Egln3tm1Vlcg
Tg(Myh6-cre)2182Mds/0
involves: 129S6/SvEvTac * FVB/N 		abnormal heart left ventricle morphology J:179490
cardiomyopathy J:179490
decreased mitochondrial number J:179490
decreased ventricle muscle contractility J:179490
increased angiogenesis J:179490
increased heart weight J:179490
myocardial fiber degeneration J:179490
premature death J:179490
Egln1tm2Fong/Egln1tm2Fong
Egln2tm2Fong/Egln2tm2Fong
Egln3tm2Fong/Egln3tm2Fong
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S6/SvEvTac * C57BL/6NCr * CD-1 		increased hematocrit J:186085
Egln2tm1Fong/Egln2tm1Fong
Egln3tm1Fong/Egln3tm1Fong
involves: 129S6/SvEvTac * C57BL/6 		abnormal autopod morphology J:132720
abnormal definitive hematopoiesis J:132720
abnormal snout morphology J:132720
abnormal splenic cell ratio J:132720
decreased litter size J:132720
enlarged liver J:132720
enlarged spleen J:132720
extramedullary hematopoiesis J:132720
increased hematocrit J:132720
increased hemoglobin content J:132720
polycythemia J:132720
reddish skin J:132720
Egln3tm1Pjr/Egln3tm1Pjr
Epas1tm1Pec/Epas1+
involves: 129S/SvEv * Swiss 		abnormal neuron physiology J:136034
abnormal superior cervical ganglion morphology J:136034
Egln3tm1Pjr/Egln3tm1Pjr
Hif1atm1Pec/Hif1a+
involves: 129S/SvEv * Swiss 		abnormal neuron physiology J:136034
abnormal superior cervical ganglion morphology J:136034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory