Agpat1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1
MGI:1932075

42 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agpat1^em1Andm/Agpat1^em1Andm C57BL/6J-Agpat1^em1Andm	decreased body size	J:338850
Agpat1^em1Andm/Agpat1^em1Andm C57BL/6J-Agpat1^em1Andm	postnatal lethality, complete penetrance	J:338850
Agpat1^{tm1.1(KOMP)Vlcg}/Agpat1⁺ B6N(Cg)-Agpat1^{tm1.1(KOMP)Vlcg}/J	decreased circulating calcium level	J:211773
	decreased circulating chloride level	J:211773
	decreased circulating glucose level	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating potassium level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased urine glucose level	J:211773
	increased urine microalbumin level	J:211773
	prolonged RR interval	J:211773
Agpat1^{tm1.1(KOMP)Vlcg}/Agpat1^{tm1.1(KOMP)Vlcg} B6N(Cg)-Agpat1^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, incomplete penetrance	J:211773
Agpat1^tm1Garg/Agpat1^tm1Garg involves: 129S6/SvEvTac * C57BL/6	abnormal enzyme/coenzyme activity	J:250301
	abnormal epididymal fat pad morphology	J:250301
	abnormal estrous cycle	J:250301
	abnormal hippocampus morphology	J:250301
	abnormal spermatid morphology	J:250301
	abnormal spermatocyte morphology	J:250301
	abnormal spermatogenesis	J:250301
	arrest of male meiosis	J:250301
	audiogenic seizures	J:250301
	normal behavior/neurological phenotype	J:250301
	decreased body weight	J:250301
	decreased circulating glucose level	J:250301
	decreased circulating insulin-like growth factor I level	J:250301
	decreased circulating leptin level	J:250301
	decreased ovulation rate	J:250301
	decreased percent body fat/body weight	J:250301
	female infertility	J:250301
	normal homeostasis/metabolism phenotype	J:250301
	hypoglycemia	J:250301
	impaired gluconeogenesis	J:250301
	increased circulating follicle stimulating hormone level	J:250301
	increased circulating luteinizing hormone level	J:250301
	increased locomotor activity	J:250301
	increased tertiary ovarian follicle number	J:250301
	increased vertical activity	J:250301
	male infertility	J:250301
	postnatal lethality, incomplete penetrance	J:250301
	premature death	J:250301
	prolonged diestrus	J:250301
	slow postnatal weight gain	J:250301

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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