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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pycard
PYD and CARD domain containing
MGI:1931465
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+
Pycardtm1Vmd/Pycardtm1Vmd
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J 		normal growth/size/body region phenotype J:260047
normal immune system phenotype J:260047
increased circulating interferon-gamma level J:260047
increased circulating interleukin-6 level J:260047
increased circulating tumor necrosis factor level J:260047
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
Pycardtm1Tno/Pycardtm1Tno
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		decreased interleukin-1 beta secretion J:172117
normal growth/size/body region phenotype J:172117
normal immune system phenotype J:172117
Nlrp1aNeut1/Nlrp1aNeut1
Pycardtm1Vmd/Pycardtm1Vmd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
Nlrp3tm1Hhf/Nlrp3+
Pycardtm1Flv/Pycardtm1Flv
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:150054
Pycardtm1Flv/Pycardtm1Flv
Slc11a1s/Slc11a1s
B6.129S5-Pycardtm1Flv 		increased susceptibility to bacterial infection J:124378
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory