Dclre1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dclre1a
DNA cross-link repair 1A
MGI:1930042

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dclre1a^tm1Remo/Dclre1a^tm1Remo involves: 129X1/SvJ	abnormal chromosome morphology	J:134461
Dclre1a^tm1Rleg/Dclre1a⁺ involves: 129S7/SvEvBrd	decreased tumor latency	J:102381
	increased histiocytic sarcoma incidence	J:102381
	increased lymphoma incidence	J:102381
	increased tumor incidence	J:102381
	premature death	J:102381
Dclre1a^tm1Rleg/Dclre1a^tm1Rleg involves: 129S7/SvEvBrd	decreased cell proliferation	J:102381
	decreased tumor latency	J:102381
	normal immune system phenotype	J:102381
	increased adenoma incidence	J:102381
	increased histiocytic sarcoma incidence	J:102381
	increased lung adenoma incidence	J:102381
	increased lymphoma incidence	J:102381
	increased ovarian teratoma incidence	J:102381
	increased sarcoma incidence	J:102381
	increased susceptibility to bacterial infection	J:102381
	increased susceptibility to xenobiotic induced morbidity/mortality	J:102381
	increased tumor incidence	J:102381
	premature death	J:102381
Dclre1a^tm1Roka/Dclre1a^tm1Roka Not Specified	abnormal cell physiology	J:62832
Dclre1a^tm1Roka/Dclre1a^tm1Roka Not Specified	increased susceptibility to xenobiotic induced morbidity/mortality	J:62832

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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