Asb2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Asb2
ankyrin repeat and SOCS box-containing 2
MGI:1929743

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Asb2^tm1.1Lutz/Asb2^tm1.1Lutz Tg(Mx1-cre)1Cgn/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal dendritic cell physiology	J:200966
Asb2^{tm2b(KOMP)Wtsi}/Asb2⁺ C57BL/6N-Asb2^{tm2b(KOMP)Wtsi}/Kmpc	abnormal retina blood vessel morphology	J:211773
	decreased effector memory T-helper cell number	J:211773
	decreased Ly6C-positive immature NK cell number	J:211773
	decreased total body fat amount	J:211773
	increased CD4-positive, alpha-beta T cell number	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased dendritic cell number	J:211773
	increased eosinophil cell number	J:211773
	increased Ly6C-positive immature NK cell number	J:211773
	increased Ly6C-positive mature NK cell number	J:211773
	increased Ly6C-positive NK T cell number	J:211773
	increased NK cell number	J:211773
	increased T cell number	J:211773
Asb2^{tm2b(KOMP)Wtsi}/Asb2^{tm2b(KOMP)Wtsi} C57BL/6N-Asb2^{tm2b(KOMP)Wtsi}/Kmpc	abnormal embryo size	J:211773
	abnormal pericardium morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	embryonic growth retardation	J:211773
	pale yolk sac	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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