Pus1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pus1
pseudouridine synthase 1
MGI:1929237

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pus1^em1(IMPC)J/Pus1^em1(IMPC)J C57BL/6NJ-Pus1^em1(IMPC)J/Mmjax	abnormal eyelid morphology	J:211773
	abnormal iris morphology	J:211773
	abnormal iris pigmentation	J:211773
	abnormal iris transillumination	J:211773
	corneal deposits	J:211773
	corneal vascularization	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	exophthalmos	J:211773
	eye hemorrhage	J:211773
	eyelids fail to open	J:211773
	impaired pupillary reflex	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating phosphate level	J:211773
	increased thigmotaxis	J:211773
	irregularly shaped pupil	J:211773
	mydriasis	J:211773
	narrow eye opening	J:211773
	sclerocornea	J:211773
Pus1^tm1.1Mdf/Pus1^tm1.1Mdf B6.129S7(C)-Pus1^tm1.1Mdf	abnormal muscle physiology	J:237107
	decreased mitochondrial size	J:237107
	decreased skeletal muscle fiber size	J:237107
	decreased skeletal muscle mass	J:237107
	impaired exercise endurance	J:237107
	slow postnatal weight gain	J:237107

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23