Il17b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il17b
interleukin 17B
MGI:1928397

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il17b^em1Cya/Il17b^em1Cya C57BL/6-Il17b^em1Cya	abnormal cytokine level	J:339366
	increased macrophage cytokine production	J:339366
	increased neutrophil cell number	J:339366
	increased susceptibility to induced colitis	J:339366
Il17b^{Gt(371C12)Cmhd}/Il17b^{Gt(371C12)Cmhd} B6.129-Il17b^{Gt(371C12)Cmhd}	abnormal chemokine secretion	J:229778
	abnormal interleukin secretion	J:229778
	decreased interleukin-4 secretion	J:229778
	increased eosinophil cell number	J:229778
	increased interleukin-1 beta secretion	J:229778
	increased interleukin-5 secretion	J:229778
	increased interleukin-6 secretion	J:229778
	increased interleukin-13 secretion	J:229778
	increased susceptibility to bacterial infection	J:229778
	increased susceptibility to induced colitis	J:229778
	increased susceptibility to weight loss	J:229778
	increased T-helper 2 cell number	J:229778
	increased tumor necrosis factor secretion	J:229778

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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