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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mtor
mechanistic target of rapamycin kinase
MGI:1928394
26 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst/Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst
involves: C57BL/6
abnormal cellular extravasation J:178759
decreased vascular permeability J:178759
impaired neutrophil recruitment J:178759
Eif4ebp1tm1Nso/Eif4ebp1tm1Nso
Mtortm1.1Gcon/Mtortm1.1Gcon
A1cfTg(Myh6-cre/Esr1*)1Jmk/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
abnormal autophagy J:163763
abnormal mitochondrial physiology J:163763
cardiac interstitial fibrosis J:163763
normal cardiovascular system phenotype J:163763
decreased cardiomyocyte apoptosis J:163763
premature death J:163763
Emx1tm1(cre)Ito/Emx1+
Tg(CAG-Mtor*)#Atai/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * ICR
abnormal cerebral cortex morphology J:211789
decreased neuronal precursor cell number J:211789
increased neuron apoptosis J:211789
small hippocampus J:211789
Mtorchino/Mtorchino
Rasgrp1m1Anu/Rasgrp1m1Anu
involves: C57BL/6JAnu * C57BL/6JSfdAnu * CBA/J
normal hematopoietic system phenotype J:207898
normal immune system phenotype J:207898
MtorGt(OST92090)Lex/Mtor+
Ptentm1Rps/Pten+
involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6
extended life span J:144810
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-Mtor*)#Atai/0
involves: C57BL/6 * DBA/2 * ICR
abnormal cerebral cortex morphology J:211789
abnormal neuron morphology J:211789
hypoactivity J:211789
megacephaly J:211789
microgliosis J:211789
neurodegeneration J:211789
neuronal cytoplasmic inclusions J:211789
postnatal growth retardation J:211789
postnatal lethality J:211789
premature death J:211789
seizures J:211789
thickened cerebral cortex J:211789

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory