Afg3l1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Afg3l1
AFG3-like AAA ATPase 1
MGI:1928277

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Afg3l1^tm1.1Arte/Afg3l1^tm1.1Arte Afg3l2^tm1Arte/Afg3l2^tm1Arte Gt(ROSA)26Sor^tm1Lrsn/Gt(ROSA)26Sor⁺ Tg(Plp1-cre/ERT)3Pop/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N	abnormal dermal layer morphology	J:237410
	abnormal melanoblast morphology	J:237410
	abnormal mitochondrial physiology	J:237410
	abnormal oligodendrocyte morphology	J:237410
	abnormal oligodendrocyte physiology	J:237410
	abnormal Schwann cell morphology	J:237410
	abnormal sciatic nerve morphology	J:237410
	decreased melanocyte number	J:237410
	demyelination	J:237410
	dilated mitochondrion	J:237410
Afg3l1^tm1.1Arte/Afg3l1^tm1.1Arte Afg3l2^tm1Arte/Afg3l2^tm1Arte Tg(Plp1-cre/ERT)3Pop/0 involves: C57BL/6J * C57BL/6N	abnormal brain white matter morphology	J:237410
	abnormal coat/hair pigmentation	J:237410
	abnormal spinal cord white matter morphology	J:237410
	astrocytosis	J:237410
	axon degeneration	J:237410
	decreased body fat mass	J:237410
	decreased body weight	J:237410
	demyelination	J:237410
	impaired coordination	J:237410
	microgliosis	J:237410

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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