Pglyrp2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pglyrp2
peptidoglycan recognition protein 2
MGI:1928099

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pglyrp2^tm1Lky/Pglyrp2^tm1Lky involves: 129S4/SvJae * C57BL/6	abnormal macrophage physiology	J:159600
	abnormal tumor necrosis factor level	J:159600
	decreased circulating interleukin-6 level	J:159600
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:159600
Pglyrp2^tm1Rdz/Pglyrp2^tm1Rdz C.129S-Pglyrp2^tm1Rdz	abnormal circulating chemokine level	J:178054
Pglyrp2^tm1Rdz/Pglyrp2^tm1Rdz C.129S-Pglyrp2^tm1Rdz	decreased susceptibility to induced arthritis	J:178054
Pglyrp2^tm1Rdz/Pglyrp2^tm1Rdz involves: 129S/SvEv * BALB/c	abnormal chemokine secretion	J:178053
	abnormal crypts of Lieberkuhn morphology	J:178053
	abnormal gut flora balance	J:178053
	abnormal intestinal epithelium morphology	J:178053
	abnormal intestinal goblet cell morphology	J:178053
	abnormal intestinal mucosa morphology	J:178053
	gastrointestinal hemorrhage	J:178053
	increased interleukin-6 secretion	J:178053
	increased susceptibility to induced colitis	J:178053
	increased susceptibility to xenobiotic induced morbidity/mortality	J:178053
	intestinal ulcer	J:178053
	weight loss	J:178053

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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