Inpp5e Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Inpp5e
inositol polyphosphate-5-phosphatase E
MGI:1927753

37 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Inpp5e^m1Tc/Inpp5e^m1Tc involves: C57BL/6J * FVB/N	abnormal nervous system morphology	J:186861
	abnormal neural tube morphology	J:186861
	anophthalmia	J:186861
	exencephaly	J:186861
	microphthalmia	J:186861
Inpp5e^{tm1.1(KOMP)Vlcg}/Inpp5e⁺ C57BL/6N-Inpp5e^{tm1.1(KOMP)Vlcg}/Ucd	eye hemorrhage	J:211773
Inpp5e^{tm1.1(KOMP)Vlcg}/Inpp5e^{tm1.1(KOMP)Vlcg} C57BL/6N-Inpp5e^{tm1.1(KOMP)Vlcg}/MbpMmucd	abnormal craniofacial morphology	J:211773
	abnormal embryo size	J:211773
	abnormal eye morphology	J:211773
	abnormal forebrain morphology	J:211773
	abnormal hindbrain morphology	J:211773
	abnormal limb morphology	J:211773
	abnormal midbrain morphology	J:211773
	abnormal neural tube closure	J:211773
	anophthalmia	J:211773
	edema	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
Inpp5e^{tm1.1(KOMP)Vlcg}/Inpp5e^{tm1.1(KOMP)Vlcg} C57BL/6N-Inpp5e^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Inpp5e^tm1.1Ssch/Inpp5e^tm1.2Ssch Tg(CAG-cre/Esr1)5Amc/0 involves: 129S1/Sv 129X1/SvJ * C57BL/6 * CBA	abnormal retina photoreceptor layer morphology	J:152712
	increased body weight	J:152712
	kidney cortex cyst	J:152712
Inpp5e^tm1.2Ssch/Inpp5e^tm1.2Ssch involves: 129S1/Sv * 129X1/SvJ	abnormal cilium morphology	J:152712
	abnormal eye development	J:152712
	abnormal metacarpal bone morphology	J:152712
	abnormal phalanx morphology	J:152712
	abnormal renal glomerular capsule morphology	J:152712
	abnormal renal tubule epithelial cell primary cilium morphology	J:152712
	anencephaly	J:152712
	anophthalmia	J:152712
	cleft palate	J:152712
	delayed endochondral bone ossification	J:152712
	embryonic lethality during organogenesis, incomplete penetrance	J:152712
	exencephaly	J:152712
	kidney cortex cyst	J:152712
	lethality throughout fetal growth and development, incomplete penetrance	J:152712
	neonatal lethality, complete penetrance	J:152712
	palatal shelf hypoplasia	J:152712
	palatal shelves fail to meet at midline	J:152712
	polycystic kidney	J:152712
	postaxial polydactyly	J:152712
	split sternum	J:152712

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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