60 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mbtps1Gt(PST115)Byg/Mbtps1+ involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, incomplete penetrance	J:146454
Mbtps1Gt(PST115)Byg/Mbtps1Gt(PST115)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal germ layer development	J:70273
	embryonic lethality at implantation, complete penetrance	J:70273
	inner cell mass degeneration	J:70273
Mbtps1Gt(PST115)Byg/Mbtps1wrt involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:146454
Mbtps1m2Btlr/Mbtps1m2Btlr C57BL/6J-Mbtps1m2Btlr	irregular coat pigmentation	J:274663
Mbtps1tm1.1Jdh/Mbtps1tm1.1Jdh involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	preweaning lethality, complete penetrance	J:72930
Mbtps1tm1Jdh/Mbtps1+ Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S6/SvEvTac * C57BL/6 * CD-1	abnormal appendicular skeleton morphology	J:258274
	abnormal axial skeleton morphology	J:258274
	abnormal bone ossification	J:258274
	abnormal compact bone thickness	J:258274
	decreased body size	J:258274
Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal bone mineralization	J:135374
	abnormal chest morphology	J:135374
	abnormal limb morphology	J:135374
	abnormal long bone hypertrophic chondrocyte zone	J:135374
	abnormal skeleton development	J:135374
	abnormal skeleton morphology	J:135374
	abnormal skeleton physiology	J:135374
	chondrodystrophy	J:135374
	decreased birth body size	J:135374
	distended abdomen	J:135374
	failure of endochondral bone ossification	J:135374
	neonatal lethality, complete penetrance	J:135374
	protruding tongue	J:135374
	short basicranium	J:135374
	short mandible	J:135374
	short maxilla	J:135374
	small cranium	J:135374
Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Mx1-cre)29-4Her/0 involves: 129S6/SvEvTac * C57BL/6J * SJL	abnormal intestinal lipid absorption	J:72930
	abnormal lipid homeostasis	J:72930
	decreased circulating cholesterol level	J:72930
	decreased circulating triglyceride level	J:72930
	decreased liver triglyceride level	J:72930
Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 involves: 129S6/SvEvTac * C57BL/6 * CD-1	abnormal appendicular skeleton morphology	J:258274
	abnormal axial skeleton morphology	J:258274
	abnormal bone marrow cell morphology/development	J:258274
	abnormal bone ossification	J:258274
	abnormal skeleton development	J:258274
	decreased body size	J:258274
	decreased bone mineral density	J:258274
	decreased bone mineralization	J:258274
	decreased compact bone thickness	J:258274
	decreased compact bone volume	J:258274
	decreased osteoblast cell number	J:258274
	decreased trabecular bone volume	J:258274
	decreased volumetric bone mineral density	J:258274
	decreased width of hypertrophic chondrocyte zone	J:258274
	delayed endochondral bone ossification	J:258274
	fragile skeleton	J:258274
	increased chondrocyte apoptosis	J:258274
	scoliosis	J:258274
Mbtps1wrt/Mbtps1wrt C57BL/6J-Mbtps1wrt	abnormal cell physiology	J:123123
	abnormal coat/hair pigmentation	J:123123, J:146454
	decreased circulating cholesterol level	J:94077, J:123123
	decreased circulating HDL cholesterol level	J:123123
	decreased cytotoxic T cell cytolysis	J:94077
	decreased susceptibility to bacterial infection	J:123123
	hypopigmentation	J:94077, J:123123, J:146454
	increased circulating LDL cholesterol level	J:123123
	increased interleukin-1 beta secretion	J:146454
	increased interleukin-6 secretion	J:146454
	increased susceptibility to Herpesvirales infection	J:94077, J:123123
	increased susceptibility to induced colitis	J:146454
	increased susceptibility to xenobiotic induced morbidity/mortality	J:146454
	reduced female fertility	J:123123