43 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd274tm1.1Lex/Cd274tm1.1Lex involves: 129S5/SvEvBrd	abnormal cytokine secretion	J:126829
	decreased CD8-positive, alpha-beta T cell number	J:126829
	increased susceptibility to experimental autoimmune encephalomyelitis	J:126829
Cd274tm1Igu/Cd274+ involves: 129 * C57BL/6 * CBA/CaJ	lethality throughout fetal growth and development, incomplete penetrance	J:100544
Cd274tm1Lpc/Cd274tm1Lpc B6.129S-Cd274tm1Lpc	abnormal CD8-positive, alpha-beta T cell physiology	J:89781
	decreased T cell apoptosis	J:89781
	normal hematopoietic system phenotype	J:89781
	increased activated T cell number	J:89781
	increased CD8-positive, alpha-beta T cell number	J:89781
	increased susceptibility to autoimmune disorder	J:89781
Cd274tm1Lpc/Cd274tm1Lpc C.129S-Cd274tm1Lpc	abnormal regulatory T cell physiology	J:165841
	abnormal T follicular helper cell physiology	J:165841
	decreased germinal center B cell number	J:165841
	decreased IgG1 level	J:165841
	decreased IgG2a level	J:165841
	decreased interleukin-17 secretion	J:165841
	decreased plasma cell number	J:165841
	decreased T-helper 17 cell number	J:165841
	normal immune system phenotype	J:165841
	increased interferon-gamma secretion	J:165841
	increased interleukin-4 secretion	J:165841
	increased susceptibility to induced arthritis	J:165841
	increased T cell proliferation	J:165841
Cd274tm1Lpc/Cd274tm1Lpc involves: 129S/SvEv	abnormal chemokine secretion	J:158023
	hyperresponsive to tactile stimuli	J:158023
	increased susceptibility to injury	J:158023
	increased tumor necrosis factor secretion	J:158023
Cd274tm1Lpc/Cd274tm1Lpc involves: 129S/SvEv * C57BL/6	abnormal dendritic cell physiology	J:152305
	abnormal T cell morphology	J:136330
	abnormal T-helper 1 cell differentiation	J:162539
	decreased susceptibility to Riboviria infection	J:136330
	decreased susceptibility to Riboviria infection induced morbidity/mortality	J:136330
	decreased T cell apoptosis	J:136330
	decreased T helper 1 cell number	J:162539
	increased CD8-positive, alpha-beta T cell number	J:152305
	increased IgG1 level	J:162539
	increased IgG2c level	J:162539
	increased susceptibility to bacterial infection	J:162539
	increased susceptibility to bacterial infection induced morbidity/mortality	J:162539
	increased susceptibility to experimental autoimmune encephalomyelitis	J:142815
	increased T cell number	J:142815
Cd274tm1Shr/Cd274tm1Shr C.B6-Cd274tm1Shr	abnormal interleukin secretion	J:123785
	increased interferon-gamma secretion	J:123785
	increased susceptibility to autoimmune diabetes	J:123785
Cd274tm1Shr/Cd274tm1Shr involves: C57BL/6	abnormal CD4-positive, alpha beta T cell morphology	J:91480
	abnormal CD8-positive, alpha beta T cell morphology	J:91480
Cd274tm2Shr/Cd274tm2Shr involves: 129/Sv * 129S4/SvJae	abnormal cytokine secretion	J:113851
	decreased susceptibility to parasitic infection	J:113851