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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sp2
Sp2 transcription factor
MGI:1926162
28 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Sp2tm1.1Htg/Sp2+
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL
abnormal cerebral hemisphere morphology J:194076
abnormal rostral migratory stream morphology J:194076
decreased body size J:194076
decreased hippocampus volume J:194076
decreased neuronal precursor proliferation J:194076
postnatal growth retardation J:194076
small olfactory bulb J:194076
Sp2tm1.1Htg/Sp2tm1.1Htg
involves: 129
abnormal cell cycle J:194076
Sp2tm1.1Htg/Sp2tm1.1Htg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal cortical plate morphology J:194076
abnormal cortical ventricular zone morphology J:194076
abnormal embryonic/fetal subventricular zone morphology J:194076
abnormal neuron differentiation J:194076
prenatal lethality, incomplete penetrance J:194076
Sp2tm1.1Htg/Sp2tm1.1Htg
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL
abnormal cell cycle J:194076
abnormal cerebral hemisphere morphology J:194076
abnormal neuron differentiation J:194076
abnormal rostral migratory stream morphology J:194076
decreased body size J:194076
decreased hippocampus volume J:194076
decreased neuronal precursor proliferation J:194076
hydrocephaly J:194076
postnatal growth retardation J:194076
postnatal lethality, incomplete penetrance J:194076
premature death J:194076
small olfactory bulb J:194076
Sp2tm1.1Sus/Sp2tm1.1Sus
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:158671
Sp2tm1.2Sus/Sp2tm1.2Sus
involves: 129P2/OlaHsd * C57BL/6
abnormal embryo turning J:158671
absent fibroblast proliferation J:158671
decreased embryo size J:158671
embryonic growth retardation J:158671
embryonic lethality during organogenesis, complete penetrance J:158671
open neural tube J:158671
Sp2tm1Sus/Sp2tm1Sus
involves: 129P2/OlaHsd * C57BL/6
decreased fetal size J:158671
fetal growth retardation J:158671
hemorrhage J:158671
lethality throughout fetal growth and development, incomplete penetrance J:158671
postnatal lethality, complete penetrance J:158671

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory