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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rictor
RPTOR independent companion of MTOR, complex 2
MGI:1926007
53 phenotypes from 8 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
RictorGt(RRR347)Byg/RictorGt(RRR347)Byg
involves: 129P2/OlaHsd
abnormal placenta morphology J:137592
embryonic growth retardation J:137592
embryonic lethality during organogenesis, complete penetrance J:137592
thick placenta labyrinth J:137592
RictorGt(RRR347)Byg/RictorGt(RRR347)Byg
involves: 129P2/OlaHsd * C57BL/6J
embryonic lethality during organogenesis, complete penetrance J:113443
Rictortm1.1Klg/Rictortm1.1Klg
Tg(Mx1-cre)1Cgn/0
B6.Cg-Rictortm1.1Klg Tg(Mx1-cre)1Cgn
abnormal double-negative T cell morphology J:189736
decreased DN1 thymic pro-T cell number J:189736
decreased DN2 thymocyte number J:189736
decreased DN3 thymocyte number J:189736
decreased DN4 thymocyte number J:189736
decreased double-positive T cell number J:189736
decreased single-positive T cell number J:189736
decreased T cell proliferation J:189736
decreased thymus weight J:189736
normal hematopoietic system phenotype J:189736
normal immune system phenotype J:189736
increased double-negative T cell number J:189736
thymus hypoplasia J:189736
Rictortm1.1Mgn/Rictortm1.1Mgn
Tg(Ins2-cre)25Mgn/0
involves: 129S6/SvEvTac * BALB/c * C57BL/6 * DBA
abnormal glucose homeostasis J:170129
abnormal pancreatic beta cell physiology J:170129
decreased insulin secretion J:170129
decreased pancreatic beta cell mass J:170129
decreased pancreatic beta cell proliferation J:170129
hyperglycemia J:170129
impaired glucose tolerance J:170129
Rictortm1.1Mgn/Rictortm1.2Mgn
Meox2tm1(cre)Sor/Meox2+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N * SJL
lethality throughout fetal growth and development, incomplete penetrance J:119564
Rictortm1.1Mnh/Rictortm1.1Mnh
Tg(Fabp4-cre)1Rev/0
B6.Cg-Rictortm1.1Mnh Tg(Fabp4-cre)1Rev
decreased adiponectin level J:150064
enlarged pancreatic islets J:150064
improved glucose tolerance J:150064
increased body length J:150064
increased bone mineral content J:150064
increased circulating cholesterol level J:150064
increased circulating insulin level J:150064
increased circulating insulin-like growth factor I level J:150064
increased epididymal fat pad weight J:150064
increased heart weight J:150064
increased kidney weight J:150064
increased lean body mass J:150064
increased liver weight J:150064
increased pancreas weight J:150064
increased spleen weight J:150064
increased susceptibility to weight gain J:150064
insulin resistance J:150064
macrovesicular hepatic steatosis J:150064
Rictortm1.2Mgn/Rictortm1.2Mgn
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL
abnormal placenta labyrinth morphology J:119564
abnormal placental labyrinth vasculature morphology J:119564
decreased cell proliferation J:119564
decreased embryo size J:119564
embryonic lethality during organogenesis, complete penetrance J:119564
Rictortm1.2Mgn/Rictortm1.3Mgn
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL
abnormal placenta labyrinth morphology J:119564
abnormal placental labyrinth vasculature morphology J:119564
decreased embryo size J:119564
embryonic lethality during organogenesis, complete penetrance J:119564
Rictortm1.3Mgn/Rictortm1.3Mgn
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
abnormal placenta labyrinth morphology J:119564
abnormal placental labyrinth vasculature morphology J:119564
decreased embryo size J:119564
embryonic lethality during organogenesis, complete penetrance J:119564
Rictortm1Mgn/Rictortm1Mgn
involves: 129S6/SvEvTac * C57BL/6
abnormal placenta labyrinth morphology J:119564
hydrops fetalis J:119564
lethality throughout fetal growth and development, complete penetrance J:119564
small placenta J:119564
Rictortm1Rueg/Rictortm1Rueg
Tg(ACTA1-cre)1Mll/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
increased body weight J:143748
normal mortality/aging J:143748
normal muscle phenotype J:143748

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory