About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Heg1
heart development protein with EGF-like domains 1
MGI:1924696
17 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ccm2Gt(RRG051)Byg/Ccm2+
Heg1tm1Mlkn/Heg1+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		abnormal cardinal vein morphology J:146528
abnormal dorsal aorta morphology J:146528
abnormal vascular endothelial cell development J:146528
abnormal vasculogenesis J:146528
dilated aortic sac J:146528
embryonic growth retardation J:146528
embryonic lethality during organogenesis, complete penetrance J:146528
hemopericardium J:146528
pericardial edema J:146528
Ccm2Gt(RRG051)Byg/Ccm2+
Heg1tm1Mlkn/Heg1tm1Mlkn
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal pharyngeal arch artery morphology J:187714
embryonic lethality during organogenesis, complete penetrance J:187714
Ccm2ltm1Mlkn/Ccm2ltm1Mlkn
Ccm2Gt(RRG051)Byg/Ccm2+
Heg1tm1Mlkn/Heg1tm1Mlkn
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal cardiovascular development J:187714
prenatal lethality, incomplete penetrance J:187714
Ccm2ltm1Mlkn/Ccm2ltm1Mlkn
Ccm2tm1Mlkn/Ccm2+
Heg1tm1Mlkn/Heg1tm2.1Mlkn
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6 * SJL 		prenatal lethality, incomplete penetrance J:187714
Ccm2ltm1Mlkn/Ccm2ltm1Mlkn
Heg1tm1Mlkn/Heg1tm1Mlkn
involves: 129 * C57BL/6 		decreased fetal cardiomyocyte proliferation J:187714
decreased ventricle muscle contractility J:187714
dilated heart atrium J:187714
embryonic lethality during organogenesis, complete penetrance J:187714
thin myocardium J:187714
trabecula carnea hypoplasia J:187714
Ccm2ltm1Mlkn/Ccm2ltm1Mlkn
Heg1tm1Mlkn/Heg1tm2.1Mlkn
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6 * SJL 		embryonic lethality during organogenesis, complete penetrance J:187714
thin myocardium J:187714
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory