Ddrgk1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddrgk1
DDRGK domain containing 1
MGI:1924256

23 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ddrgk1^em1Brle/Ddrgk1^em1Brle C57BL/6J-Ddrgk1^em1Brle	abnormal cartilage development	J:243374
	abnormal limb bud morphology	J:243374
	abnormal limb mesenchyme morphology	J:243374
	decreased erythrocyte cell number	J:243374
	embryonic lethality prior to tooth bud stage	J:243374
Ddrgk1^{tm1b(EUCOMM)Hmgu}/Ddrgk1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Ddrgk1^{tm1b(EUCOMM)Hmgu}/Rbrc	preweaning lethality, complete penetrance	J:211773
Ddrgk1^{tm1b(EUCOMM)Hmgu}/Ddrgk1^{tm1b(EUCOMM)Hmgu} involves: C57BL/6N	abnormal embryonic erythrocyte morphology	J:231701
	abnormal embryonic erythropoiesis	J:231701
	decreased common myeloid progenitor cell number	J:231701
	decreased embryo size	J:231701
	decreased erythrocyte cell number	J:231701
	decreased erythroid progenitor cell number	J:231701
	embryonic lethality during organogenesis, complete penetrance	J:231701
	increased cell death	J:231701
	liver hypoplasia	J:231701
	pallor	J:231701
Ddrgk1^{tm1c(EUCOMM)Hmgu}/Ddrgk1^{tm1c(EUCOMM)Hmgu} Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6N	abnormal embryonic erythropoiesis	J:231701
	abnormal hematopoietic stem cell physiology	J:231701
	decreased erythrocyte cell number	J:231701
	decreased granulocyte number	J:231701
	decreased hemoglobin content	J:231701
	decreased lymphocyte cell number	J:231701
	decreased monocyte cell number	J:231701
	pancytopenia	J:231701
	premature death	J:231701
	weight loss	J:231701

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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