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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Memo1
mediator of cell motility 1
MGI:1924140
57 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Memo1tm1c(EUCOMM)Wtsi/Memo1tm1c(EUCOMM)Wtsi
involves: C57BL/6 * CBA/J * SJL
abnormal craniofacial bone morphology J:233609
abnormal endochondral bone ossification J:233609
abnormal nasal bridge morphology J:233609
absent gastric milk in neonates J:233609
cleft palate J:233609
domed cranium J:233609
maxillary shelf hypoplasia J:233609
palatine bone horizontal plate hypoplasia J:233609
premaxilla hypoplasia J:233609
presphenoid bone hypoplasia J:233609
preweaning lethality, complete penetrance J:233609
small basisphenoid bone J:233609
wide coronal suture J:233609
wide metopic suture J:233609
Memo1m1Will/Memo1m1Will
involves: 129S1/SvImJ * C57BL/6J
abnormal bone ossification J:233609
abnormal cranial cartilage development J:233609
abnormal craniofacial bone morphology J:233609
abnormal cranium morphology J:233609
abnormal endochondral bone ossification J:233609
abnormal nasal bridge morphology J:233609
abnormal neurocranium morphology J:233609
abnormal otic capsule morphology J:233609
abnormal vasculogenesis J:233609
absent gastric milk in neonates J:233609
absent maxillary shelf J:233609
absent palatine bone horizontal plate J:233609
basioccipital bone hypoplasia J:233609
basisphenoid bone hypoplasia J:233609
cleft palate J:233609
decreased angiogenesis J:233609
domed cranium J:233609
embryonic lethality during organogenesis J:233609
failure of endochondral bone ossification J:233609
failure of palatal shelf elevation J:233609
generalized edema J:233609
hemorrhage J:233609
maxilla hypoplasia J:233609
palate bone hypoplasia J:233609
premaxilla hypoplasia J:233609
presphenoid bone hypoplasia J:233609
preweaning lethality, complete penetrance J:233609
Memo1tm1.1Neh/Memo1tm1.1Neh
Tg(CAG-cre/Esr1*)1Lbe/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
abnormal coat/hair pigmentation J:206626
abnormal reflex J:206626
abnormal sex gland morphology J:206626
alopecia J:206626
azoospermia J:206626
decreased body size J:206626
decreased body weight J:206626
decreased subcutaneous adipose tissue amount J:206626
decreased white adipose tissue amount J:206626
normal homeostasis/metabolism phenotype J:206626
improved glucose tolerance J:206626
increased circulating calcium level J:206626
increased circulating parathyroid hormone level J:206626
increased insulin sensitivity J:206626
increased vitamin D level J:206626
kyphosis J:206626
premature death J:206626
weight loss J:206626
Memo1tm1a(EUCOMM)Wtsi/Memo1+
C57BL/6N-Memo1tm1a(EUCOMM)Wtsi/Bay
trunk curl J:211773
Memo1tm1a(EUCOMM)Wtsi/Memo1tm1a(EUCOMM)Wtsi
C57BL/6N-Memo1tm1a(EUCOMM)Wtsi/Bay
preweaning lethality, complete penetrance J:211773
Memo1tm1b(EUCOMM)Wtsi/Memo1+
C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay
thick ventricular wall J:211773
unresponsive to tactile stimuli J:211773
Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay
abnormal embryo size J:211773
abnormal pericardium morphology J:211773
edema J:211773
hemorrhage J:211773
preweaning lethality, complete penetrance J:211773
unresponsive to tactile stimuli J:211773
Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
involves: Black Swiss * C57BL/6 * FVB/N
abnormal nasal bridge morphology J:233609
cleft secondary palate J:233609
domed cranium J:233609
preweaning lethality, complete penetrance J:233609

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory