Plekha5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plekha5
pleckstrin homology domain containing, family A member 5
MGI:1923802

28 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plekha5^em1(IMPC)Tcp/Plekha5^em1(IMPC)Tcp C57BL/6NCrl-Plekha5^em1(IMPC)Tcp/Tcp	abnormal cornea morphology	J:211773
	abnormal iris morphology	J:211773
	abnormal iris pigmentation	J:211773
	abnormal lens morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal placement of pupils	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal skin morphology	J:211773
	corneal vascularization	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	enlarged lymph nodes	J:211773
	enlarged urinary bladder	J:211773
	fused cornea and lens	J:211773
	impaired pupillary reflex	J:211773
	increased spleen weight	J:211773
	increased startle reflex	J:211773
	iris synechia	J:211773
	irregularly shaped pupil	J:211773
	mydriasis	J:211773
	narrow eye opening	J:211773
	persistence of hyaloid vascular system	J:211773
Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: C57BL/6 * C57BL/6J * SJL	abnormal male germ cell apoptosis	J:189585
Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: C57BL/6 * SJL	normal reproductive system phenotype	J:157337
Plekha5^{Tg(AMH-cre)1Flor}/Plekha5^{Tg(AMH-cre)1Flor} involves: C57BL/6 * C57BL/6J * SJL	abnormal male germ cell apoptosis	J:189585
	abnormal peroxisome physiology	J:189585
	abnormal Sertoli cell morphology	J:189585
	oxidative stress	J:189585

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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