49 phenotypes from 11 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hprt1tm3(CAG-Tbx18,-Venus)Akis/Y Tbx18tm4(cre)Akis/Tbx18+ involves: 129S1/SvImJ * NMRI	normal cardiovascular system phenotype	J:210076
	postnatal lethality, complete penetrance	J:210076
Hprt1tm4(CAG-Tbx18*,-Venus)Akis/Y Tbx18tm4(cre)Akis/Tbx18+ involves: 129S1/SvImJ * NMRI	abnormal pericardium morphology	J:210076
	abnormal sinus venosus morphology	J:210076
	normal cardiovascular system phenotype	J:210076
	decreased fetal cardiomyocyte proliferation	J:210076
	heart hypoplasia	J:210076
	lethality throughout fetal growth and development, complete penetrance	J:210076
	thin ventricle myocardium compact layer	J:210076
Tbx18tm1.1Akis/Tbx18tm1.1Akis involves: 129S1/SvImJ * NMRI	abnormal dorsal-ventral polarity of the somites	J:90513
	abnormal lumbar vertebrae morphology	J:90513
	abnormal rib morphology	J:90513
	abnormal spinal nerve morphology	J:90513
	abnormal thoracic vertebrae morphology	J:90513
	abnormal vertebrae development	J:90513
	abnormal vertebrae morphology	J:90513
	abnormal vertebral arch morphology	J:90513
	decreased birth body size	J:90513
	fused dorsal root ganglion	J:90513
	fusion of atlas and occipital bones	J:90513
	neonatal lethality, complete penetrance	J:90513
	rib fusion	J:90513
	small intervertebral disk	J:90513
Tbx18tm1.1Mwmy/Tbx18tm1.1Mwmy involves: 129 * C57BL/6J	abnormal axial skeleton morphology	J:203805
	abnormal cardiovascular development	J:203805
	abnormal chest morphology	J:203805
	abnormal coronary vessel morphology	J:203805
	abnormal epicardium morphology	J:203805
	abnormal kidney morphology	J:203805
	abnormal myocardium compact layer morphology	J:203805
	abnormal rib morphology	J:203805
	abnormal ureter morphology	J:203805
	absent intervertebral disk	J:203805
	decreased body length	J:203805
	neonatal lethality, complete penetrance	J:203805
	respiratory distress	J:203805
	rib fusion	J:203805
	small intervertebral disk	J:203805
Tbx18tm1Akis/Tbx18tm1Akis involves: 129S1/SvImJ	abnormal common cardinal vein morphology	J:122633
	abnormal heart morphology	J:122633
	abnormal vein morphology	J:122633
Tbx18tm1Akis/Tbx18tm1Akis involves: 129S1/SvImJ * NMRI	abnormal dorsal-ventral polarity of the somites	J:90513
	abnormal lumbar vertebrae morphology	J:90513
	abnormal rib morphology	J:90513
	abnormal spinal nerve morphology	J:90513
	abnormal thoracic vertebrae morphology	J:90513
	abnormal vertebrae development	J:90513
	abnormal vertebrae morphology	J:90513
	abnormal vertebral arch morphology	J:90513
	decreased birth body size	J:90513
	fused dorsal root ganglion	J:90513
	fusion of atlas and occipital bones	J:90513
	neonatal lethality, complete penetrance	J:90513
	rib fusion	J:90513
	small intervertebral disk	J:90513
Tbx18tm1Akis/Tbx18tm4(cre)Akis involves: 129S1/SvImJ	normal cardiovascular system phenotype	J:210076
Tbx18tm1Sev/Tbx18tm1.1Sev involves: 129S4/SvJaeSor	abnormal skeleton morphology	J:196480
	decreased body length	J:196480
	normal integument phenotype	J:196480
	perinatal lethality	J:196480
	respiratory distress	J:196480
Tbx18tm2Akis/Tbx18tm2Akis involves: NMRI	abnormal pleuropericardial membrane morphology	J:192889
Tg(Dll1-Tbx18)2Akis/0 involves: FVB	abnormal skeleton morphology	J:90513
	abnormal vertebrae morphology	J:90513
	abnormal vertebral pedicle morphology	J:90513
	thin ribs	J:90513
Tg(Dll1-Tbx18)2Akis/Tg(Dll1-Tbx18)2Akis involves: FVB	abnormal vertebrae morphology	J:90513
	abnormal vertebral pedicle morphology	J:90513
	thin ribs	J:90513
Tg(Dll1-Tbx18)20Akis/0 involves: FVB	abnormal skeleton morphology	J:90513
	abnormal vertebrae morphology	J:90513
	abnormal vertebral pedicle morphology	J:90513
	thin ribs	J:90513
Tg(Dll1-Tbx18)20Akis/Tg(Dll1-Tbx18)20Akis involves: FVB	abnormal dorsal-ventral polarity of the somites	J:90513
	abnormal spinal nerve morphology	J:90513
	abnormal thoracic cage shape	J:90513
	abnormal vertebrae morphology	J:90513
	abnormal vertebral pedicle morphology	J:90513
	absent proximal rib	J:90513
	decreased embryo size	J:90513
	lordosis	J:90513
	small thoracic cage	J:90513
Tg(Adipoq-cre)1Evdr/0 involves: FVB/NJ	decreased fasting circulating glucose level	J:249843
	improved glucose tolerance	J:249843