Prex2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
MGI:1923385

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prex2^em1(IMPC)Bay/Prex2^em1(IMPC)Bay C57BL/6N-Prex2^em1(IMPC)Bay/BayMmucd	thin ventricular wall	J:211773
Prex2^{Gt(AH0440)Wtsi}/Prex2^{Gt(AH0440)Wtsi} B6.129P2-Prex2^{Gt(AH0440)Wtsi}	impaired glucose tolerance	J:206382
	increased circulating glucose level	J:206382
	insulin resistance	J:206382
Prex2^{Gt(RRD186)Byg}/Prex2^{Gt(RRD186)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal Purkinje cell dendrite morphology	J:133335
	decreased body weight	J:133335
	decreased locomotor activity	J:133335
	impaired coordination	J:133335
	increased startle reflex	J:133335
	limb grasping	J:133335
	short stride length	J:133335
Prex2^{Gt(RRD186)Byg}/Prex2^{Gt(RRD186)Byg} Tg(Pcp2-EGFP)2Yuza/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal Purkinje cell dendrite morphology	J:133335

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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