Cul5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cul5
cullin 5
MGI:1922967

17 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cul5^{tm1.1(KOMP)Vlcg}/Cul5⁺ C57BL/6N-Cul5^{tm1.1(KOMP)Vlcg}/Ucd	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	increased spleen weight	J:211773
Cul5^{tm1.1(KOMP)Vlcg}/Cul5⁺ involves: C57BL/6NTac	decreased interleukin-1 alpha secretion	J:244502
	decreased interleukin-6 secretion	J:244502
	decreased susceptibility to injury	J:244502
	decreased tumor necrosis factor secretion	J:244502
Cul5^{tm1.1(KOMP)Vlcg}/Cul5^{tm1.1(KOMP)Vlcg} C57BL/6N-Cul5^{tm1.1(KOMP)Vlcg}/Ucd	abnormal embryo size	J:211773
	abnormal neural tube morphology	J:211773
	abnormal pericardium morphology	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	pallor	J:211773
	preweaning lethality, complete penetrance	J:211773
Cul5^{tm1.1(KOMP)Vlcg}/Cul5^{tm1.1(KOMP)Vlcg} involves: C57BL/6NTac	embryonic lethality, complete penetrance	J:244502

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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