Mettl5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mettl5
methyltransferase 5, N6-adenosine
MGI:1922672

37 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mettl5^{em1(IMPC)Hmgu}/Mettl5⁺ C57BL/6N-Mettl5^{em1(IMPC)Hmgu}/Ieg	abnormal auditory brainstem response	J:211773
	abnormal gait	J:211773
	decreased blood urea nitrogen level	J:211773
	increased grip strength	J:211773
	increased hematocrit	J:211773
Mettl5^{em1(IMPC)Hmgu}/Mettl5^{em1(IMPC)Hmgu} C57BL/6N-Mettl5^{em1(IMPC)Hmgu}/Ieg	abnormal auditory brainstem response	J:211773
	abnormal behavior	J:211773
	abnormal cornea morphology	J:211773
	abnormal cranium morphology	J:211773
	abnormal head morphology	J:211773
	abnormal iris morphology	J:211773
	abnormal lens morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased anxiety-related response	J:211773
	decreased body length	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
	decreased vertical activity	J:211773
	hyperactivity	J:211773
	increased grip strength	J:211773
	increased spleen weight	J:211773
	iris synechia	J:211773
	persistence of hyaloid vascular system	J:211773
Mettl5^em1Schne/Mettl5^em1Schne involves: C57BL/6NCrl	abnormal craniofacial morphology	J:289086
	abnormal nasal bone morphology	J:289086
	abnormal spermatogonia morphology	J:289086
	abnormal vitreous body morphology	J:289086
	decreased body weight	J:289086
	decreased locomotor activity	J:289086
	decreased vertical activity	J:289086
	delayed cranial suture closure	J:289086
	increased or absent threshold for auditory brainstem response	J:289086
	male infertility	J:289086
	preweaning lethality, incomplete penetrance	J:289086
	seminiferous tubule degeneration	J:289086

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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