Rspo2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rspo2
R-spondin 2
MGI:1922667

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lrp6^Gt(Ex187)Byg/Lrp6⁺ Rspo2^tm1Nuv/Rspo2^tm1Nuv involves: 129 * 129P2/OlaHsd * C57BL/6	abnormal craniofacial morphology	J:171482
	cleft palate	J:171482
	cleft upper lip	J:171482
	decreased cranium height	J:171482
	short mandible	J:171482
	short maxilla	J:171482
	short Meckel's cartilage	J:171482
Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg Rspo2^tm1Nuv/Rspo2^tm1Nuv involves: 129 * 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:171482
Rspo2^ftls/Rspo2^ftls Rspo3^tm1.1Jcob/Rspo3^tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL	abnormal digit morphology	J:188812
	abnormal forelimb morphology	J:188812
	abnormal hindlimb morphology	J:188812
	abnormal humerus morphology	J:188812
	abnormal lung morphology	J:188812
	abnormal scapula morphology	J:188812
	absent gastric milk in neonates	J:188812
	absent tibia	J:188812
	adactyly	J:188812
	bowed femur	J:188812
	brachydactyly	J:188812
	neonatal lethality, complete penetrance	J:188812
	short femur	J:188812
	short tibia	J:188812

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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