Usp20 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Usp20
ubiquitin specific peptidase 20
MGI:1921520

35 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Usp20^em1Cya/Usp20^em1Cya Not Specified	decreased body fat mass	J:299971
	decreased body weight	J:299971
	decreased circulating cholesterol level	J:299971
	decreased circulating triglyceride level	J:299971
	improved glucose tolerance	J:299971
	increased insulin sensitivity	J:299971
Usp20^em1Dalin/Usp20^em1Dalin involves: C57BL/6	abnormal circulating chemokine level	J:274572
	decreased circulating interferon-beta level	J:274572
	decreased circulating interleukin-6 level	J:274572
	decreased interferon-beta secretion	J:274572
	decreased tumor necrosis factor secretion	J:274572
	increased susceptibility to Herpesvirales infection	J:274572
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:274572
Usp20^em1Gpt/Usp20^em1Gpt Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6JGpt * DBA	abnormal circulating enzyme level	J:299971
	abnormal enzyme/coenzyme level	J:299971
	abnormal liver morphology	J:299971
	normal behavior/neurological phenotype	J:299971
	decreased body fat mass	J:299971
	decreased body weight	J:299971
	decreased circulating cholesterol level	J:299971
	decreased circulating free fatty acids level	J:299971
	decreased circulating glucose level	J:299971
	decreased circulating HDL cholesterol level	J:299971
	decreased circulating insulin level	J:299971
	decreased circulating LDL cholesterol level	J:299971
	decreased circulating triglyceride level	J:299971
	decreased circulating VLDL triglyceride level	J:299971
	decreased fasting circulating glucose level	J:299971
	decreased fat cell size	J:299971
	decreased liver cholesterol level	J:299971
	decreased liver triglyceride level	J:299971
	decreased liver weight	J:299971
	decreased white adipose tissue mass	J:299971
	normal homeostasis/metabolism phenotype	J:299971
	improved glucose tolerance	J:299971
	increased body surface temperature	J:299971
	increased energy expenditure	J:299971
	increased insulin sensitivity	J:299971
	increased oxygen consumption	J:299971
Usp20^{tm1a(EUCOMM)Hmgu}/Usp20^{tm1a(EUCOMM)Hmgu} C57BL/6N-Usp20^{tm1a(EUCOMM)Hmgu}/Wtsi	increased circulating alkaline phosphatase level	J:211773
	increased circulating chloride level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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