80 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnm1lem1Hise/Dnm1lem1Hise involves: C57BL/6J * SJL/J	abnormal dendritic spine morphology	J:291773
	abnormal synapse morphology	J:291773
	normal behavior/neurological phenotype	J:291773
	normal cellular phenotype	J:291773
	enhanced sensorimotor gating	J:291773
	increased prepulse inhibition	J:291773
Dnm1lem1Hise/Dnm1lem1Hise Tg(Thy1-EGFP)MJrs/0 involves: C57BL/6J * CBA * SJL/J	abnormal dendritic spine morphology	J:291773
	abnormal neurite morphology	J:291773
	normal cellular phenotype	J:291773
Dnm1lPy/Dnm1l+ involves: BALB/cAnNCrl * C3H/HeH	abnormal cardiac muscle relaxation	J:161510
	abnormal cardiovascular system physiology	J:161510
	abnormal cellular respiration	J:161510
	abnormal heart morphology	J:161510
	abnormal heart ventricle pressure	J:161510
	abnormal metabolism	J:161510
	abnormal mitochondrial ATP synthesis coupled electron transport	J:161510
	abnormal mitochondrial morphology	J:161510
	abnormal myocardial fiber mitochondrial morphology	J:161510
	abnormal peroxisome morphology	J:161510
	abnormal pilomotor reflex	J:161510
	ascites	J:161510
	cardiac interstitial fibrosis	J:161510
	congestive heart failure	J:161510
	decreased left ventricle systolic pressure	J:161510
	decreased mean systemic arterial blood pressure	J:161510
	decreased ventricle muscle contractility	J:161510
	dilated heart	J:161510
	dystrophic cardiac calcinosis	J:161510
	increased body size	J:161510
	increased circulating alanine transaminase level	J:161510
	increased circulating aspartate transaminase level	J:161510
	increased left ventricle diastolic pressure	J:161510
	increased myocardial fiber size	J:161510
	liver vascular congestion	J:161510
	pleural effusion	J:161510
	pulmonary vascular congestion	J:161510
	skin edema	J:161510
	tachypnea	J:161510
	thin myocardium	J:161510
	visceral vascular congestion	J:161510
Dnm1lPy/Dnm1l+ involves: BALB/cAnNCrl * C3H/HeH * C57BL/6J	congestive heart failure	J:161510
Dnm1lPy/Dnm1lPy involves: BALB/cAnNCrl * C3H/HeH	abnormal cell adhesion	J:161510
	abnormal cell physiology	J:161510
	abnormal mitochondrial morphology	J:161510
	absent fibroblast proliferation	J:161510
	caudal body truncation	J:161510
	embryonic growth retardation	J:161510
	prenatal lethality, complete penetrance	J:161510
Dnm1ltm1.1Hise/Dnm1ltm1.1Hise En1tm2(cre)Wrst/En1+ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal cerebellar Purkinje cell layer	J:153835
	abnormal cerebellum development	J:153835
	abnormal Purkinje cell mitochondrial morphology	J:153835
	absent gastric milk in neonates	J:153835
	decreased Purkinje cell number	J:153835
	postnatal lethality, complete penetrance	J:153835
	reduced cerebellar foliation	J:153835
	small cerebellum	J:153835
Dnm1ltm1.1Hise/Dnm1ltm1.2Hise En1tm2(cre)Wrst/En1+ involves: 129 * C57BL/6 * FVB/N * SJL	abnormal cerebellar Purkinje cell layer	J:153835
	abnormal cerebellum development	J:153835
	abnormal Purkinje cell mitochondrial morphology	J:153835
	absent gastric milk in neonates	J:153835
	decreased Purkinje cell number	J:153835
	postnatal lethality, complete penetrance	J:153835
	reduced cerebellar foliation	J:153835
	small cerebellum	J:153835
Dnm1ltm1.1Miha/Dnm1ltm1.1Miha Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * SJL	abnormal brain morphology	J:158142
	abnormal brain white matter morphology	J:158142
	abnormal brainstem morphology	J:158142
	abnormal mitochondrial morphology	J:158142
	abnormal neurite morphology	J:158142
	abnormal posterior cranial fossa morphology	J:158142
	abnormal subarachnoid space morphology	J:158142
	decreased CNS synapse formation	J:158142
	enlarged brain ventricles	J:158142
	forebrain hypoplasia	J:158142
	increased neuron apoptosis	J:158142
	postnatal lethality, complete penetrance	J:158142
	small cerebellum	J:158142
Dnm1ltm1.2Hise/Dnm1ltm1.2Hise involves: 129S/SvEv * C57BL/6 * FVB/N	abnormal mitochondrial morphology	J:153835
	abnormal myocardial fiber physiology	J:153835
	absent trophoblast giant cells	J:153835
	decreased apoptosis	J:153835
	decreased embryo size	J:153835
	decreased fibroblast proliferation	J:153835
	embryonic lethality during organogenesis, complete penetrance	J:153835
	internal hemorrhage	J:153835
Dnm1ltm1.2Miha/Dnm1ltm1.2Miha involves: C57BL/6J	abnormal heart development	J:158142
	abnormal mitochondrial morphology	J:158142
	abnormal peroxisome morphology	J:158142
	decreased embryo size	J:158142
	decreased embryonic neuroepithelium thickness	J:158142
	decreased fibroblast proliferation	J:158142
	delayed hepatic development	J:158142
	embryonic lethality during organogenesis, incomplete penetrance	J:158142
	increased brain apoptosis	J:158142
	increased mitochondrial size	J:158142
	prenatal lethality, complete penetrance	J:158142
Dnm1ltm1b(KOMP)Wtsi/Dnm1l+ C57BL/6N-Dnm1ltm1b(KOMP)Wtsi/Ics	abnormal coat/ hair morphology	J:211773
	abnormal cornea morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal vitreous body morphology	J:211773
	persistence of hyaloid vascular system	J:211773
Dnm1ltm1b(KOMP)Wtsi/Dnm1ltm1b(KOMP)Wtsi C57BL/6N-Dnm1ltm1b(KOMP)Wtsi/Ics	preweaning lethality, complete penetrance	J:211773