Psmb11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Psmb11
proteasome (prosome, macropain) subunit, beta type, 11
MGI:1921152

28 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Psmb11^{em1(IMPC)Ccpcz}/Psmb11^{em1(IMPC)Ccpcz} C57BL/6NCrl-Psmb11^{em1(IMPC)Ccpcz}/Ccpcz	abnormal colon morphology	J:211773
	abnormal digit morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal ileum morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	decreased effector memory T-helper cell number	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	increased CD4-positive NK T cell number	J:211773
	increased CD4-positive, alpha-beta T cell number	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	increased effector memory T-helper cell number	J:211773
	increased kidney weight	J:211773
	increased memory-marker CD4-positive NK T cell number	J:211773
	increased NK T cell number	J:211773
	increased T-helper cell number	J:211773
	small testis	J:211773
Psmb11^{tm1(Psmb8)Khog}/Psmb11⁺ involves: C57BL/6	decreased CD8-positive, alpha-beta T cell number	J:196156
Psmb11^{tm1(Psmb8)Khog}/Psmb11^{tm1(Psmb8)Khog} involves: C57BL/6	abnormal CD8-positive, alpha beta T cell morphology	J:196156
	abnormal self tolerance	J:196156
	abnormal T cell differentiation	J:196156
	abnormal T cell receptor V(D)J recombination	J:196156
	decreased CD8-positive, alpha-beta T cell number	J:196156
	decreased memory T cell number	J:196156
	increased T cell proliferation	J:196156
Psmb11^tm1Smta/Psmb11^tm1Smta involves: C57BL/6 * CBA	decreased CD8-positive, alpha-beta T cell number	J:121869

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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