Fam161a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fam161a
family with sequence similarity 161, member A
MGI:1921123

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fam161a^{Gt(462E7)Cmhd}/Fam161a^{Gt(462E7)Cmhd} involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal electroretinogram waveform feature	J:214319
	abnormal photoreceptor connecting cilium morphology	J:214319
	abnormal photoreceptor outer segment morphology	J:214319
	abnormal retina photoreceptor morphology	J:214319
	abnormal vision	J:214319
	decreased a-wave amplitude	J:214319
	decreased b-wave amplitude	J:214319
	disorganized photoreceptor outer segment	J:214319
	increased a-wave implicit time	J:214319
	increased b-wave implicit time	J:214319
	increased retina apoptosis	J:214319
	increased susceptibility to age-related retinal degeneration	J:214319
	microgliosis	J:214319
	retina outer nuclear layer degeneration	J:214319
	retina photoreceptor degeneration	J:214319
	thin retina outer nuclear layer	J:214319
Fam161a^{tm1b(KOMP)Wtsi}/Fam161a^{tm1b(KOMP)Wtsi} C57BL/6N-Fam161a^{tm1b(KOMP)Wtsi}/J	decreased coping response	J:211773
	decreased exploration in new environment	J:211773
	increased circulating sodium level	J:211773
	increased grip strength	J:211773
	increased heart rate	J:211773
	increased heart weight	J:211773
	increased lean body mass	J:211773
	increased startle reflex	J:211773
	shortened RR interval	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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