Tmem135 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem135
transmembrane protein 135
MGI:1920009

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(CAG-Tmem135)#Aike/0 involves: C57BL/6J * FVB/NJ	abnormal mitochondrial morphology	J:237184
	abnormal mitochondrial physiology	J:237184
	decreased mitochondrial size	J:237184
	increased mitochondrial fission	J:237184
	oxidative stress	J:237184
Tmem135^em1Aike/Tmem135^fun025 C57BL/6J-Tmem135^em1Aike/Tmem135^fun025	abnormal retina morphology	J:237184
Tmem135^fun025/Tmem135^fun025 C57BL/6J-Tmem135^fun025	abnormal cone electrophysiology	J:237184
	abnormal mitochondrial morphology	J:237184
	abnormal mitochondrial physiology	J:237184
	abnormal respiratory electron transport chain	J:237184
	abnormal retina bipolar cell morphology	J:237184
	abnormal retina morphology	J:237184
	abnormal rod electrophysiology	J:237184
	decreased mitochondrial fission	J:237184
	decreased mitochondrial number	J:237184
	increased mitochondrial size	J:237184
	increased susceptibility to injury	J:237184
	lipofuscinosis	J:237184
	oxidative stress	J:237184
	retina gliosis	J:237184
	retina photoreceptor degeneration	J:237184
	retina pigment epithelium hyperplasia	J:237184
	thin retina outer nuclear layer	J:237184

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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