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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pgam5
phosphoglycerate mutase family member 5
MGI:1919792
37 phenotypes from 4 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pgam5tm1a(EUCOMM)Wtsi/Pgam5tm1a(EUCOMM)Wtsi
involves: C57BL/6N
abnormal gait J:225345
abnormal mitochondrial crista morphology J:225345
abnormal mitochondrial morphology J:225345
abnormal mitochondrial physiology J:225345
abnormal motor coordination/balance J:225345
akinesia J:225345
bradykinesia J:225345
decreased dopamine level J:225345
decreased vertical activity J:225345
normal homeostasis/metabolism phenotype J:225345
loss of dopaminergic neurons J:225345
neuron degeneration J:225345
oxidative stress J:225345
short stride length J:225345
Pgam5tm1b(EUCOMM)Wtsi/Pgam5tm1b(EUCOMM)Wtsi
C57BL/6N-Pgam5tm1b(EUCOMM)Wtsi/Ics
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased erythrocyte cell number J:211773
decreased exploration in new environment J:211773
decreased total retina thickness J:211773
increased circulating creatinine level J:211773
increased mean corpuscular volume J:211773
short tibia J:211773
Pgam5tm1c(EUCOMM)Wtsi/Pgam5tm1c(EUCOMM)Wtsi
involves: C57BL/6N
no abnormal phenotype detected J:240016
Pgam5tm1d(EUCOMM)Wtsi/Pgam5tm1d(EUCOMM)Wtsi
involves: C57BL/6N
abnormal interleukin-1 beta secretion J:240016
abnormal macrophage activation involved in immune response J:240016
abnormal mitochondrial morphology J:240016
abnormal mitochondrial shape J:240016
abnormal redox activity J:240016
normal cellular phenotype J:240016
decreased body size J:240016
decreased body weight J:240016
decreased interleukin-1 beta secretion J:240016
decreased survivor rate J:240016
premature death J:240016
prenatal lethality, incomplete penetrance J:240016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory