25 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spink5em1(IMPC)J/Spink5em1(IMPC)J C57BL/6NJ-Spink5em1(IMPC)J/Mmjax	preweaning lethality, complete penetrance	J:211773
Spink5m1Btlr/Spink5m1Btlr involves: C57BL/6J	flaky skin	J:183755
	increased neutrophil cell number	J:183755
	scaly skin	J:183755
	skin lesions	J:183755
Spink5tm1Drh/Spink5tm1Drh involves: 129P2/OlaHsd * C57BL/6	abnormal corneocyte envelope morphology	J:95549
	abnormal epidermal layer morphology	J:95549
	dehydration	J:95549
	hyperkeratosis	J:95549
	impaired skin barrier function	J:95549
	neonatal lethality, complete penetrance	J:95549
Spink5tm1Hov/Spink5tm1Hov involves: 129P2/OlaHsd * FVB	abnormal epidermal layer morphology	J:96435
	abnormal epidermis stratum corneum morphology	J:96435
	abnormal epidermis stratum granulosum morphology	J:96435
	abnormal hair follicle morphology	J:96435
	abnormal hair shaft morphology	J:96435
	abnormal vibrissa follicle morphology	J:96435
	abnormal vibrissa morphology	J:96435
	acanthosis	J:96435
	decreased skin tensile strength	J:96435
	epidermal desquamation	J:96435
	hyperkeratosis	J:96435
	impaired skin barrier function	J:96435
	neonatal lethality, complete penetrance	J:96435
	parakeratosis	J:96435
	reddish skin	J:96435
	scaly skin	J:96435
	skin lesions	J:96435
	sparse vibrissae	J:96435
Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove/Spink5Tn(Pgk2-sb10,sb-Tyr)1498Ove involves: FVB/N	abnormal epidermis stratum corneum morphology	J:93050
	abnormal epidermis stratum granulosum morphology	J:93050
	blistering	J:93050
	dehydration	J:93050
	impaired skin barrier function	J:93050
	normal integument phenotype	J:93050
	neonatal lethality, complete penetrance	J:93050