Pinx1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
MGI:1919650

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pinx1^tm1.1Kplu/Pinx1⁺ Trp53^tm1Brd/Trp53⁺ involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	increased carcinoma incidence	J:171997
	increased hepatocellular carcinoma incidence	J:171997
	increased liver tumor incidence	J:171997
	increased lung carcinoma incidence	J:171997
	increased lung tumor incidence	J:171997
	increased lymphoma incidence	J:171997
	increased mammary gland tumor incidence	J:171997
	increased ovary tumor incidence	J:171997
	increased tumor incidence	J:171997
	premature death	J:171997
Pinx1^tm1.1Kplu/Pinx1⁺ Trp53^tm1Brd/Trp53^tm1Brd involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	increased carcinoma incidence	J:171997
	increased gastrointestinal tumor incidence	J:171997
	increased hepatocellular carcinoma incidence	J:171997
	increased liver tumor incidence	J:171997
	increased lung carcinoma incidence	J:171997
	increased lymphoma incidence	J:171997
	increased mammary gland tumor incidence	J:171997
	premature death	J:171997
Pinx1^tm1.1Kplu/Pinx1⁺ Tert^tm1Leah/Tert^tm1Leah involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N	normal cellular phenotype	J:171997

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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