1700016L21Rik Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

1700016L21Rik
RIKEN cDNA 1700016L21 gene
MGI:1919458

49 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 B6.FVB-1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}	abnormal circulating cytokine level	J:194800
	abnormal susceptibility to infection	J:194800
	decreased dendritic cell number	J:194800
	decreased neutrophil cell number	J:194800
	impaired neutrophil recruitment	J:194800
	increased monocyte cell number	J:194800
	increased neutrophil cell number	J:194800
	increased susceptibility to bacterial infection	J:194800
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 B6.FVB-1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/J	abnormal NK cell physiology	J:96123
	abnormal NK T cell physiology	J:96123
	decreased circulating interferon-gamma level	J:96123
	decreased circulating interleukin-12 level	J:96123
	decreased dendritic cell number	J:96123, J:100867, J:113232
	decreased interferon-gamma secretion	J:96123
	decreased interleukin-4 secretion	J:96123
	decreased interleukin-12b secretion	J:125611
	normal immune system phenotype	J:96123, J:122114
	impaired natural killer cell mediated cytotoxicity	J:125611
	increased susceptibility to induced morbidity/mortality	J:113232
	sepsis	J:113232
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 C.FVB-1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}	abnormal CD8-positive, alpha-beta T cell differentiation	J:93488
	abnormal T cell activation	J:93488
	decreased CD8-positive, alpha-beta T cell number	J:93488
	decreased cytotoxic T cell cytolysis	J:93488
	decreased dendritic cell number	J:93488
	increased neutrophil cell number	J:194800
	premature death	J:93488
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 C.FVB-1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/J	abnormal NK cell physiology	J:96123
	decreased circulating interferon-gamma level	J:96123
	decreased circulating interleukin-12 level	J:96123
	decreased dendritic cell number	J:96123
	decreased interferon-gamma secretion	J:96123
	normal immune system phenotype	J:96123
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 involves: C57BL/6 * FVB/N	abnormal alveolar macrophage morphology	J:137452
	decreased dendritic cell number	J:137452
	decreased interferon-gamma secretion	J:137452
	increased susceptibility to Orthomyxoviridae infection	J:137452
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 involves: FVB/N	abnormal response to infection	J:189122
	decreased gamma-delta T cell number	J:193548
	decreased interleukin-17 secretion	J:193548
	decreased leukocyte cell number	J:193548
	decreased neutrophil cell number	J:193548
	decreased physiological sensitivity to xenobiotic	J:193548
	decreased susceptibility to bacterial infection	J:210086
	decreased T cell number	J:193548
1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 NOD.FVB-1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/Jdk	abnormal professional antigen presenting cell physiology	J:137009
	cachexia	J:137009
	decreased dendritic cell number	J:137009
	decreased macrophage cell number	J:137009
	decreased NK T cell number	J:137009
	decreased susceptibility to autoimmune diabetes	J:137009
	normal endocrine/exocrine gland phenotype	J:137009
	increased interferon-gamma secretion	J:137009
	increased tumor necrosis factor secretion	J:137009
	insulitis	J:137009
	premature death	J:137009
Siglec1^{tm1(HBEGF)Mtka}/Siglec1^{tm1(HBEGF)Mtka} 1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/? involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal dendritic cell physiology	J:123958
	abnormal immune system physiology	J:123958
	abnormal immune tolerance	J:123958
	abnormal macrophage physiology	J:123958
	abnormal metallophilic macrophage morphology	J:123958
	abnormal spleen marginal zone macrophage morphology	J:123958
Tg(Ins2-TFRC/OVA)296Wehi/0 1700016L21Rik^{Tg(Itgax-HBEGF/EGFP)57Lan}/0 involves: C57BL/6 * FVB	decreased T cell proliferation	J:122114

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