Slc39a4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc39a4
solute carrier family 39 (zinc transporter), member 4
MGI:1919277

43 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc39a4^{tm1.1(KOMP)Wtsi}/Slc39a4⁺ C57BL/6N-Slc39a4^{tm1.1(KOMP)Wtsi}/MbpMmucd	abnormal forebrain development	J:211773
	abnormal hindbrain development	J:211773
	abnormal midbrain development	J:211773
	abnormal neural tube closure	J:211773
Slc39a4^{tm1.1(KOMP)Wtsi}/Slc39a4⁺ C57BL/6N-Slc39a4^{tm1.1(KOMP)Wtsi}/Ucd	increased fasting circulating glucose level	J:211773
Slc39a4^{tm1.1(KOMP)Wtsi}/Slc39a4^{tm1.1(KOMP)Wtsi} C57BL/6N-Slc39a4^{tm1.1(KOMP)Wtsi}/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
Slc39a4^{tm1.1(KOMP)Wtsi}/Slc39a4^{tm1.1(KOMP)Wtsi} C57BL/6N-Slc39a4^{tm1.1(KOMP)Wtsi}/Ucd	preweaning lethality, complete penetrance	J:211773
Slc39a4^tm1Gka/Slc39a4⁺ involves: 129S1/Sv * C57BL/6 * FVB/N	abnormal craniofacial development	J:125096
	abnormal embryo development	J:125096
	abnormal head morphology	J:125096
	abnormal heart left ventricle morphology	J:125096
	abnormal skeleton morphology	J:125096
	anophthalmia	J:125096
	decreased body size	J:125096
	decreased embryo size	J:125096
	embryonic growth retardation	J:125096
	embryonic lethality during organogenesis, incomplete penetrance	J:125096
	exencephaly	J:125096
	hydrocephaly	J:125096
	maternal effect	J:125096
	postnatal lethality, incomplete penetrance	J:125096
	thick interventricular septum	J:125096
Slc39a4^tm1Gka/Slc39a4^tm1Gka involves: 129S1/Sv * C57BL/6 * FVB/N	embryonic lethality during organogenesis, complete penetrance	J:125096
Slc39a4^tm2Gka/Slc39a4^tm2Gka Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal copper level	J:187178
	abnormal liver morphology	J:187178
	abnormal mineral homeostasis	J:187178
	abnormal Paneth cell morphology	J:187178
	abnormal small intestinal crypt cell proliferation	J:187178
	abnormal small intestinal villus morphology	J:187178
	abnormal small intestine crypts of Lieberkuhn morphology	J:187178
	abnormal zinc homeostasis	J:187178
	decreased bone mass	J:187178
	decreased intestinal iron level	J:187178
	decreased intestine copper level	J:187178
	decreased liver copper level	J:187178
	decreased muscle weight	J:187178
	increased liver copper level	J:187178
	increased liver iron level	J:187178
	lethality at weaning, complete penetrance	J:187178
	postnatal growth retardation	J:187178
	premature death	J:187178
	weight loss	J:187178

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