Gimap6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gimap6
GTPase, IMAP family member 6
MGI:1918876

30 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gimap6^tm1.1Gwb/Gimap6^tm1.1Gwb Tg(CD2-icre)4Kio/0 involves: C57BL/6 * C57BL/10 * CBA/Ca	abnormal autophagy	J:262059
	abnormal leukocyte morphology	J:262059
	abnormal mitochondrial morphology	J:262059
	abnormal mitophagy	J:262059
	abnormal T cell physiology	J:262059
	decreased B cell number	J:262059
	decreased T cell number	J:262059
	increased B cell number	J:262059
	increased T cell apoptosis	J:262059
Gimap6^{tm1a(KOMP)Wtsi}/Gimap6^{tm1a(KOMP)Wtsi} C57BL/6N-Gimap6^{tm1a(KOMP)Wtsi}/Wtsi	decreased CD4-negative NK T cell number	J:211773
	decreased circulating amylase level	J:211773
	decreased lean body mass	J:211773
	decreased memory-marker CD4-negative NK T cell number	J:211773
	impaired glucose tolerance	J:211773
	increased circulating chloride level	J:211773
	increased memory-marker CD4-negative NK T cell number	J:211773
	increased monocyte cell number	J:211773
	increased total body fat amount	J:211773
Gimap6^{tm1b(KOMP)Wtsi}/Gimap6^{tm1b(KOMP)Wtsi} C57BL/6N-Gimap6^{tm1b(KOMP)Wtsi}/J	abnormal sleep behavior	J:211773
	decreased circulating iron level	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating sodium level	J:211773
	increased fasting circulating glucose level	J:211773
	increased heart weight	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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