Sfpq Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
MGI:1918764

15 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sfpq^{Gt(BC0256)Wtsi}/Sfpq⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal circardian behavior entrainment	J:189236
Sfpq^{Gt(BC0256)Wtsi}/Sfpq^{Gt(BC0256)Wtsi} involves: 129P2/OlaHsd * C57BL/6J	lethality, complete penetrance	J:189236
Sfpq^tm1.1Takea/Sfpq^tm1.1Takea Tg(Nes-cre)1Kln/0 involves: C57BL/6 * CBA/JNCrlj * SJL	abnormal brain morphology	J:271630
	abnormal cerebral cortex morphology	J:271630
	abnormal thalamus morphology	J:271630
	enlarged third ventricle	J:271630
	increased neuron apoptosis	J:271630
	microphthalmia	J:271630
	normal nervous system phenotype	J:271630
	postnatal lethality	J:271630
	small thalamus	J:271630
	thin cerebral cortex	J:271630
Sfpq^tm1.2Takea/Sfpq^tm1.2Takea involves: C57BL/6 * CBA/JNCrlj	embryonic lethality prior to organogenesis	J:271630
Sfpq^{tm1a(EUCOMM)Wtsi}/Sfpq⁺ C57BL/6N-Sfpq^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal snout morphology	J:211773
	decreased circulating amylase level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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