Dlg5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dlg5
discs large MAGUK scaffold protein 5
MGI:1918478

28 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dlg5^{tm1b(EUCOMM)Wtsi}/Dlg5⁺ C57BL/6N-Dlg5^{tm1b(EUCOMM)Wtsi}/Ucd	abnormal brain morphology	J:211773
	anophthalmia	J:211773
	hemorrhage	J:211773
	hydrocephaly	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Dlg5^{tm1b(EUCOMM)Wtsi}/Dlg5^{tm1b(EUCOMM)Wtsi} C57BL/6N-Dlg5^{tm1b(EUCOMM)Wtsi}/Ucd	anophthalmia	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Dlg5^tm1Vv/Dlg5^tm1Vv involves: 129 * C57BL/6	abnormal brain morphology	J:124940
	abnormal cerebral aqueduct morphology	J:124940
	abnormal ependyma morphology	J:124940
	abnormal gait	J:124940
	abnormal head morphology	J:124940
	abnormal kidney collecting duct morphology	J:124940
	abnormal neuron differentiation	J:124940
	abnormal papillary duct morphology	J:124940
	abnormal postnatal subventricular zone morphology	J:124940
	abnormal renal tubule morphology	J:124940
	abnormal third ventricle morphology	J:124940
	abnormal ureter morphology	J:124940
	dilated kidney collecting duct	J:124940
	dilated lateral ventricle	J:124940
	hydrocephaly	J:124940
	increased blood urea nitrogen level	J:124940
	increased brain size	J:124940
	kidney cyst	J:124940
	postnatal growth retardation	J:124940
	ureter stenosis	J:124940

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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