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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Abraxas1
BRCA1 A complex subunit
MGI:1917931
11 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
Abraxas1tm1.1Bwng/Abraxas1+
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
increased histiocytic sarcoma incidence J:269823
increased lung adenocarcinoma incidence J:269823
increased lymphoma incidence J:269823
increased tumor incidence J:269823
premature death J:269823
Abraxas1tm1.1Bwng/Abraxas1tm1.1Bwng
involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
abnormal cell nucleus morphology J:269823
abnormal double-strand DNA break repair J:269823
increased cellular sensitivity to DNA damaging agents J:269823
increased cellular sensitivity to gamma-irradiation J:269823
increased lymphoma incidence J:269823
increased mortality induced by gamma-irradiation J:269823
increased tumor incidence J:269823
premature death J:269823
spontaneous chromosome breakage J:269823

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory